Identification of DNA-binding proteins (DNA-BPs) is a hot issue in protein science due to its key role in various biological processes. These processes are highly concerned with DNA-binding protein types. DNA-BPs are classified into single-stranded D...
Computer methods and programs in biomedicine
Nov 2, 2019
The early identification of malignant pulmonary nodules is critical for a better lung cancer prognosis and less invasive chemo or radio therapies. Nodule malignancy assessment done by radiologists is extremely useful for planning a preventive interve...
IMPORTANCE: Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown pro...
Computer methods and programs in biomedicine
Oct 31, 2019
BACKGROUND AND OBJECTIVE: In most patients presenting with respiratory symptoms, the findings of chest radiography play a key role in the diagnosis, management, and follow-up of the disease. Consolidation is a common term in radiology, which indicate...
OBJECTIVE: Models for predicting preterm birth generally have focused on very preterm (28-32 weeks) and moderate to late preterm (32-37 weeks) settings. However, extreme preterm birth (EPB), before the 28th week of gestational age, accounts for the m...
Computer methods and programs in biomedicine
Oct 23, 2019
BACKGROUND AND OBJECTIVES: Malignant lymphomas are cancers of the immune system and are characterized by enlarged lymph nodes that typically spread across many different sites. Many different histological subtypes exist, whose diagnosis is typically ...
Protein-protein interaction (PPI) extraction from published scientific literature provides additional support for precision medicine efforts. Meanwhile, knowledge bases (KBs) contain huge amounts of structured information of protein entities and thei...
Ovarian cancer (OC) is a common cause of cancer death among women worldwide, so there is a pressing need to identify factors influencing OC mortality. Much OC patient clinical data is publicly accessible via the Broad Institute Cancer Genome Atlas (T...
BACKGROUND: Manually curating standardized phenotypic concepts such as Human Phenotype Ontology (HPO) terms from narrative text in electronic health records (EHRs) is time consuming and error prone. Natural language processing (NLP) techniques can fa...
BACKGROUND AND OBJECTIVE: Cerebral stroke has become a significant global public health issue in recent years. The ideal solution to this concern is to prevent in advance by controlling related metabolic factors. However, it is difficult for medical ...