AIMC Topic: Deep Learning

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Decoding whole-genome mutational signatures in 37 human pan-cancers by denoising sparse autoencoder neural network.

Oncogene
Millions of somatic mutations have recently been discovered in cancer genomes. These mutations in cancer genomes occur due to internal and external mutagenesis forces. Decoding the mutational processes by examining their unique patterns has successfu...

Diagnostic evaluation of a deep learning model for optical diagnosis of colorectal cancer.

Nature communications
Colonoscopy is commonly used to screen for colorectal cancer (CRC). We develop a deep learning model called CRCNet for optical diagnosis of CRC by training on 464,105 images from 12,179 patients and test its performance on 2263 patients from three in...

Electrical Impedance Tomography-Based Abdominal Subcutaneous Fat Estimation Method Using Deep Learning.

Computational and mathematical methods in medicine
This paper proposes a deep learning method based on electrical impedance tomography (EIT) to estimate the thickness of abdominal subcutaneous fat. EIT for evaluating the thickness of abdominal subcutaneous fat is an absolute imaging problem that aims...

Deep learning for EEG-based Motor Imagery classification: Accuracy-cost trade-off.

PloS one
Electroencephalography (EEG) datasets are often small and high dimensional, owing to cumbersome recording processes. In these conditions, powerful machine learning techniques are essential to deal with the large amount of information and overcome the...

Practical Applications of Deep Learning To Impute Heterogeneous Drug Discovery Data.

Journal of chemical information and modeling
Contemporary deep learning approaches still struggle to bring a useful improvement in the field of drug discovery because of the challenges of sparse, noisy, and heterogeneous data that are typically encountered in this context. We use a state-of-the...

Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times.

eLife
Dopamine (DA) neurons are to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulat...

Deep learning based methods for gamma ray interaction location estimation in monolithic scintillation crystal detectors.

Physics in medicine and biology
In this work, we explore deep learning based techniques using the information from mean detector response functions (MDRFs) as a new method to estimate gamma ray interaction location in monolithic scintillation crystal detectors. Compared with search...