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Discriminant Analysis

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An unsupervised feature learning framework for basal cell carcinoma image analysis.

Artificial intelligence in medicine
OBJECTIVE: The paper addresses the problem of automatic detection of basal cell carcinoma (BCC) in histopathology images. In particular, it proposes a framework to both, learn the image representation in an unsupervised way and visualize discriminati...

Discriminative analysis of Parkinson's disease based on whole-brain functional connectivity.

PloS one
Recently, there has been an increasing emphasis on applications of pattern recognition and neuroimaging techniques in the effective and accurate diagnosis of psychiatric or neurological disorders. In the present study, we investigated the whole-brain...

RSTFC: A Novel Algorithm for Spatio-Temporal Filtering and Classification of Single-Trial EEG.

IEEE transactions on neural networks and learning systems
Learning optimal spatio-temporal filters is a key to feature extraction for single-trial electroencephalogram (EEG) classification. The challenges are controlling the complexity of the learning algorithm so as to alleviate the curse of dimensionality...

A Recurrent Probabilistic Neural Network with Dimensionality Reduction Based on Time-series Discriminant Component Analysis.

IEEE transactions on neural networks and learning systems
This paper proposes a probabilistic neural network (NN) developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of high-dimension...

Bayes optimal template matching for spike sorting - combining fisher discriminant analysis with optimal filtering.

Journal of computational neuroscience
Spike sorting, i.e., the separation of the firing activity of different neurons from extracellular measurements, is a crucial but often error-prone step in the analysis of neuronal responses. Usually, three different problems have to be solved: the d...

Learning machines and sleeping brains: Automatic sleep stage classification using decision-tree multi-class support vector machines.

Journal of neuroscience methods
BACKGROUND: Sleep staging is a critical step in a range of electrophysiological signal processing pipelines used in clinical routine as well as in sleep research. Although the results currently achievable with automatic sleep staging methods are prom...

Improving the Mann-Whitney statistical test for feature selection: an approach in breast cancer diagnosis on mammography.

Artificial intelligence in medicine
OBJECTIVE: This work addresses the theoretical description and experimental evaluation of a new feature selection method (named uFilter). The uFilter improves the Mann-Whitney U-test for reducing dimensionality and ranking features in binary classifi...

Multivariate decoding of cerebral blood flow measures in a clinical model of on-going postsurgical pain.

Human brain mapping
Recent reports of multivariate machine learning (ML) techniques have highlighted their potential use to detect prognostic and diagnostic markers of pain. However, applications to date have focussed on acute experimental nociceptive stimuli rather tha...

A comparison of machine learning methods for classification using simulation with multiple real data examples from mental health studies.

Statistical methods in medical research
BACKGROUND: Recent literature on the comparison of machine learning methods has raised questions about the neutrality, unbiasedness and utility of many comparative studies. Reporting of results on favourable datasets and sampling error in the estimat...

Machine Learning Analysis of Single-Voxel Proton MR Spectroscopy for Differentiating Solitary Fibrous Tumors and Meningiomas.

NMR in biomedicine
Solitary fibrous tumor (SFT), formerly known as hemangiopericytoma, is an uncommon brain tumor often confused with meningioma on MRI. Unlike meningiomas, SFTs exhibit a myoinositol peak on magnetic resonance spectroscopy (MRS). This study aimed to de...