AIMC Topic: Disease Progression

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Alzheimer's disease risk prediction using machine learning for survival analysis with a comorbidity-based approach.

Scientific reports
Alzheimer's disease (AD) presents a pressing global health challenge, demanding improved strategies for early detection and understanding its progression. In this study, we address this need by employing survival analysis techniques to predict transi...

Predictive Modeling of Osteonecrosis of the Femoral Head Progression Using MobileNetV3_Large and Long Short-Term Memory Network: Novel Approach.

JMIR medical informatics
BACKGROUND: The assessment of osteonecrosis of the femoral head (ONFH) often presents challenges in accuracy and efficiency. Traditional methods rely on imaging studies and clinical judgment, prompting the need for advanced approaches. This study aim...

Artificial intelligence algorithms for differentiating pseudoprogression from true progression in high-grade gliomas: A systematic review and meta-analysis.

Neurosurgical review
Differentiating pseudoprogression (PsP) from true progression (TP) in high-grade glioma (HGG) patients is still challenging and critical for effective treatment management. This meta-analysis evaluates the diagnostic accuracy of artificial intelligen...

Initiation of antifibrotic treatment in fibrosing interstitial lung disease: is the clock ticking till proven progression?

European respiratory review : an official journal of the European Respiratory Society
Several interstitial lung diseases (ILDs) with different aetiologies and pathogenic mechanisms may exhibit a progressive behaviour, similar to idiopathic pulmonary fibrosis, with comparable functional decline and early mortality. Progressive pulmonar...

Beyond unimodal analysis: Multimodal ensemble learning for enhanced assessment of atherosclerotic disease progression.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Atherosclerosis is a leading cardiovascular disease typified by fatty streaks accumulating within arterial walls, culminating in potential plaque ruptures and subsequent strokes. Existing clinical risk scores, such as systematic coronary risk estimat...

NAFLD progression in metabolic syndrome: a Raman spectroscopy and machine learning approach in an animal model.

The Analyst
Nonalcoholic fatty liver disease (NAFLD) is emerging as the leading cause of chronic liver disease in many regions, particularly in association with the rising prevalence of Metabolic syndrome (MetS), affecting more than 30% of the population worldwi...

SPP1 + macrophages facilitate pancreatic cancer progression via ITGB6-mediated interactions: evidence from integrated multi-omics analysis and experimental validation.

Immunologic research
Basement membranes (BMs) and tumor-associated macrophages (TAMs) are crucial stromal components in pancreatic cancer (PC), critically influencing disease progression. Bulk and single-cell RNA-seq (scRNA-seq) data were acquired from publicly available...

Multilevel Hydrangea-like Heterogeneous Oxides Enabling COVID-19 Progression Surveillance via Metabolic Fingerprints.

Analytical chemistry
Coronavirus disease 2019 (COVID-19), a global pandemic infectious disease, requires early diagnosis and dynamic monitoring to enable timely intervention and reduce the risks of adverse outcomes. To support these needs, we developed an advanced metabo...

Selenium exposure on breast cancer risk and progression: Comprehensive analysis identifies MSRB1 as a novel therapeutic target.

Ecotoxicology and environmental safety
BACKGROUND: Breast cancer (BRCA) is the most common malignancy in women worldwide. Selenium (Se), a crucial trace element, significantly impacts BRCA patient survival, although its roles in tumorigenesis, the tumor immune microenvironment (TIME), and...

Collaborative assessment of the risk of postoperative progression in early-stage non-small cell lung cancer: a robust federated learning model.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: While the TNM staging system provides valuable insights into the extent of disease, predicting postoperative progression in early-stage non-small cell lung cancer (NSCLC) remains a significant challenge. An effective bioimaging prognostic...