OBJECTIVE: The LungFlag risk prediction model uses individualized clinical variables to identify individuals at high-risk of non-small cell lung cancer (NSCLC) for screening with low-dose computed tomography (LDCT). This study evaluates the cost-effe...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 15, 2025
Breast cancer is one of the most common tumors in women, and early screening can significantly reduce mortality rates. Meanwhile, accurately identifying HER2-positive and HER2-negative subtypes of breast cancer is critical for helping doctors determi...
UNLABELLED: Recent studies have reported increases in early-onset cancer cases (diagnosed less than 50 years of age) and raised questions about whether the increase is related to earlier diagnosis from nonspecific medical tests as reflected by decrea...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Nov 1, 2025
Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its poor prognosis and late diagnosis. Biomarkers are essential in enhancing diagnostic accuracy, prognostic assessments, and therapeutic strategies, thereby address...
European heart journal. Cardiovascular Imaging
Oct 30, 2025
AIMS: Epicardial adipose tissue (EAT) is a metabolically active fat depot associated with coronary atherosclerosis and cardiovascular (CV) risk. While EAT is a known prognostic marker in lung cancer screening, its sex-specific prognostic value remain...
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Oct 3, 2025
BACKGROUND: The Cancer Screening Research Network is a new clinical trials network funded by the NCI. The first Cancer Screening Research Network study, the Vanguard Study (VS), will assess the feasibility of using multi-cancer detection (MCD) tests ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Sep 5, 2025
Lung cancer remains one of the deadliest malignancies worldwide, highlighting the need for highly sensitive and minimally invasive early diagnostic methods. Near-infrared spectroscopy (NIRS) offers unique advantages in probing molecular vibrational i...
Cancer prevention research (Philadelphia, Pa.)
Sep 2, 2025
UNLABELLED: Cervical cancer is one of the most common cancers in women. Despite progress in prevention and success in early detection through cytologic screening and human papillomavirus (HPV) detection, there remains a challenge in triaging women ap...
BACKGROUND: Recently, western countries have built evidence on mammographic artificial Intelligence-computer-aided diagnosis (AI-CADx) systems; however, their effectiveness has not yet been sufficiently validated in Japanese women. In this study, we ...
Atypia of Undetermined Significance (AUS), classified as Category III in the Bethesda Thyroid Cytopathology Reporting System, presents significant diagnostic challenges for clinicians. This study aims to develop a clinical decision support system tha...
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