Neoadjuvant therapy has been widely used in breast cancer, but treatment response varies among individuals. We conducted multiomic profiling on tumor samples from 149 Chinese patients with breast cancer across ERHER2, ERHER2, and ERHER2 subtypes, cat...
BACKGROUND: People experiencing homelessness have worse oral health outcomes and a notable health informational asymmetry compared to the general population. Screening programs present a viable option for this population; however, barriers to access,...
Critical network states and neural plasticity enable adaptive behavior in dynamic environments, supporting efficient information processing and experience-dependent learning. Synaptic-weight-based Hebbian plasticity and homeostatic synaptic scaling a...
BACKGROUND: Managing multiple long-term conditions (MLTC) is complex. Clinical management guidelines are typically focused on individual conditions and lack a robust evidence base for patients with MLTC. MLTC management is largely delivered in primar...
BACKGROUND: Artificial intelligence (AI) holds significant promise for medical applications, particularly in coronary computed tomography angiography (CTA). We assessed the knowledge, attitudes, and practices (KAP) of cardiovascular health care perso...
Kidney transplantation (KT) is an effective treatment for end-stage renal disease; however, the lifelong immunosuppressive regimen increases the risk of infection, presenting significant clinical, and economic challenges. Identifying predictive bioma...
Early lung cancer invasive detection is important for further treatment and saving lives. In clinical practice, lung tumor invasiveness (LTI) detection is very challenging, imaging-based automatic prediction algorithms offer a non-invasive approach. ...
Postnatal adverse outcomes can often be explained and predicted by the pathological evaluation of the placenta after a pregnancy. However, placenta whole-slide image (WSI) analysis is not performed systematically due to the specialized skills require...
BACKGROUND: Major depressive disorder (MDD) is a prevalent and severe psychiatric condition for which objective diagnostic tools are lacking. Heart rate variability (HRV), an index of autonomic nervous system (ANS) function, has shown potential for d...
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