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Deep learning-based classification of lymphedema and other lower limb edema diseases using clinical images.

Scientific reports
Lymphedema is a chronic condition characterized by lymphatic fluid accumulation, primarily affecting the limbs. Its diagnosis is challenging due to symptom overlap with conditions like chronic venous insufficiency (CVI), deep vein thrombosis (DVT), a...

Predicting metabolic dysfunction associated steatotic liver disease using explainable machine learning methods.

Scientific reports
Early and accurate identification of patients at high risk of metabolic dysfunction-associated steatotic liver disease (MASLD) is critical to prevent and improve prognosis potentially. We aimed to develop and validate an explainable prediction model ...

Leveraging machine learning in precision medicine to unveil organochlorine pesticides as predictive biomarkers for thyroid dysfunction.

Scientific reports
Exposure to organochlorine pesticides (OCPs) poses significant health risks, including cancer, endocrine dysregulation, neurological disorders, and reproductive disruption. This study investigates the association between OCP exposure and thyroid dist...

Predicting PD-L1 status in NSCLC patients using deep learning radiomics based on CT images.

Scientific reports
Radiomics refers to the utilization of automated or semi-automated techniques to extract and analyze numerous quantitative features from medical images, such as computerized tomography (CT) or magnetic resonance imaging (MRI) scans. This study aims t...

Learning-based 3D human kinematics estimation using behavioral constraints from activity classification.

Nature communications
Inertial measurement units offer a cost-effective, portable alternative to lab-based motion capture systems. However, measuring joint angles and movement trajectories with inertial measurement units is challenging due to signal drift errors caused by...

Oxidative Stress Markers and Prediction of Severity With a Machine Learning Approach in Hospitalized Patients With COVID-19 and Severe Lung Disease: Observational, Retrospective, Single-Center Feasibility Study.

JMIR formative research
BACKGROUND: Serious pulmonary pathologies of infectious, viral, or bacterial origin are accompanied by inflammation and an increase in oxidative stress (OS). In these situations, biological measurements of OS are technically difficult to obtain, and ...

Cost-Effectiveness Analysis of a Machine Learning-Based eHealth System to Predict and Reduce Emergency Department Visits and Unscheduled Hospitalizations of Older People Living at Home: Retrospective Study.

JMIR formative research
BACKGROUND: Dependent older people or those losing their autonomy are at risk of emergency hospitalization. Digital systems that monitor health remotely could be useful in reducing these visits by detecting worsening health conditions earlier. Howeve...

Clinical-level screening of sleep apnea syndrome with single-lead ECG alone is achievable using machine learning with appropriate time windows.

Sleep & breathing = Schlaf & Atmung
PURPOSE: To establish a simple and noninvasive screening test for sleep apnea (SA) that imposes less burden on potential patients. The specific objective of this study was to verify the effectiveness of past and future single-lead electrocardiogram (...

Detecting arousals and sleep from respiratory inductance plethysmography.

Sleep & breathing = Schlaf & Atmung
PURPOSE: Accurately identifying sleep states (REM, NREM, and Wake) and brief awakenings (arousals) is essential for diagnosing sleep disorders. Polysomnography (PSG) is the gold standard for such assessments but is costly and requires overnight monit...

Development of a Machine Learning Algorithm to Predict Abnormalities in Serum Phosphate in a Large Oncology Cohort.

JCO clinical cancer informatics
PURPOSE: Serum phosphate is commonly measured in oncology patients because of the relationship between oncologic conditions and treatments with abnormal phosphate. All patients attending our institution, a large specialist oncology center, have a sta...