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Predicting time-to-first cancer diagnosis across multiple cancer types.
Scientific reports
Jul 9, 2025
Cancer causes over 10 million deaths annually worldwide, with 40.5% of Americans expected to be diagnosed in their lifetime. Early detection is critical; for liver cancer, survival rates improve from 4 to 37% when caught early. However, predicting ti...
Advantages and effectiveness of AI three-dimensional reconstruction technology in the preoperative planning of total hip arthroplasty.
Scientific reports
Jul 9, 2025
In order to explore the application effect of artificial intelligence (AI) 3D reconstruction technology in total hip arthroplasty (THA), this study included a total of 109 patients with unilateral femoral head ischemic necrosis. According to the preo...
Integrating deep learning in stride-to-stride muscle activity estimation of young and old adults with wearable inertial measurement units.
Scientific reports
Jul 9, 2025
Deep learning has become powerful and yet versatile tool that allows for the extraction of complex patterns from rich datasets. One field that can benefits from this advancement is human gait analysis. Conventional gait analysis requires a specialize...
A hybrid deep learning model EfficientNet with GRU for breast cancer detection from histopathology images.
Scientific reports
Jul 9, 2025
Breast cancer remains a significant global health challenge among women, with histopathological image analysis playing a critical role in early detection. However, existing diagnostic models often struggle to extract complex patterns from high-resolu...
Multidomain Behavioral Change Digital Coaching for Chronic Disease Management in Patients With Type 2 Diabetes: Framework Development and Preliminary Evaluation.
JMIR formative research
Jul 9, 2025
BACKGROUND: Unhealthy lifestyle behaviors have been identified as a major cause of numerous health issues, with a steady global increase in their prevalence. Addressing this challenge requires comprehensive behavioral changes to promote the adoption ...
Using Natural Language Processing to Describe the Use of an Online Community for Abortion During 2022: Dynamic Topic Modeling Analysis of Reddit Posts.
JMIR infodemiology
Jul 9, 2025
BACKGROUND: Abortion access in the United States has been in a state of rapid change and increasing restriction since the Dobbs v Jackson Women's Health Organization decision from the US Supreme Court in June 2022. With further constraints on access ...
Artificial Intelligence-Enabled Facial Privacy Protection for Ocular Diagnosis: Development and Validation Study.
Journal of medical Internet research
Jul 9, 2025
BACKGROUND: Facial biometric data, while valuable for clinical applications, poses substantial privacy and security risks.
Association Between COVID-19 During Pregnancy and Preterm Birth by Trimester of Infection: Retrospective Cohort Study Using Large-Scale Social Media Data.
Journal of medical Internet research
Jul 9, 2025
BACKGROUND: Preterm birth, defined as birth at <37 weeks of gestation, is the leading cause of neonatal death globally and the second leading cause of infant mortality in the United States. There is mounting evidence that COVID-19 infection during pr...
Machine learning-based online web calculator predicts the risk of sarcopenic obesity in older adults.
Aging clinical and experimental research
Jul 9, 2025
BACKGROUND: Sarcopenic obesity (SO) has a higher risk of adverse health events compared to having obesity or sarcopenia alone due to the dual burden of both muscle loss and fat gain. The prevalence of SO is progressively increasing as the population ...
Integrated Nanopore and short-read RNA sequencing identifies dysregulation of METTL3- m6A modifications in endocrine therapy- sensitive and resistant breast cancer cells.
Functional & integrative genomics
Jul 9, 2025
The role of epitranscriptomic changes in the development of acquired endocrine therapy (ET)- resistance in estrogen receptor α (ER) expressing breast cancer (BC) is unknown. We tested the hypothesis that inhibition of METTL3, the methyltransferase re...
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