Clinical pharmacology in drug development
Jun 8, 2015
BACKGROUND: LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppression of total testosterone (TT) concentration. The objective of the present analysis was to define ...
BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia, and a major public health burden associated with significant morbidity and mortality. Automatic detection of AF could substantially help in early diagnosis, management and co...
Patients suffering from atrial fibrillation can be classified into different subtypes, according to the temporal pattern of the arrhythmia and its recurrence. Nowadays, clinicians cannot differentiate a priori between the different subtypes, and pati...
IEEE transactions on neural networks and learning systems
Aug 15, 2014
We explore a properly interconnected set of Kuramoto type oscillators that results in a new associative-memory network configuration, which includes second- and third-order additional terms in the Fourier expansion of the network's coupling. Investig...
Neural networks : the official journal of the International Neural Network Society
Jun 5, 2014
We investigated the organization of a recurrent network under ongoing synaptic plasticity using a model of neural oscillators coupled by dynamic synapses. In this model, the coupling weights changed dynamically, depending on the timing between the os...
The Journal of the Acoustical Society of America
Mar 1, 2025
Whales generate vocalizations which may, deliberately or not, encode caller identity cues. In this study, we analyze calls produced by Bryde's whales and recorded by ocean-bottom arrays of hydrophones deployed close to the Costa Rica Rift in the Pana...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
This study presents an approach for estimating gaps in arterial diameter using flow velocity obtained from spectral Doppler data. We utilize short-time Fourier transform in conjunction with deep learning models designed for spectrograms to estimate a...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Graph neural networks show strong capability of learning spatial relationships between channels. In recent studies, they greatly advanced automatic epileptic seizures detection via multi-channels scalp electroencephalography (EEG). In this work, we u...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Peripheral nerve blocking (PNB) via ultrasound (US) imaging offers the advantages of non-invasiveness, nonionizing radiation, and real-time visualization. However, the high cost of 3D US makes the clinicians to imagine the anatomical volume from 2D s...
Recent advances in inflammation & allergy drug discovery
Jan 1, 2024
BACKGROUND: Diseases are medical situations that are allied with specific signs and symptoms. A disease may be instigated by internal dysfunction or external factors like pathogens. Cerebrovascular disease can progress from diverse causes, comprising...