AIMC Topic: Glutathione

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Neuroprotective role of 6-Gingerol-rich fraction of Zingiber officinale (Ginger) against acrylonitrile-induced neurotoxicity in male Wistar rats.

Journal of basic and clinical physiology and pharmacology
Background Acrylonitrile (AN) is a neurotoxin that is widely used to manufacture synthetic fibres, plastics and beverage containers. Recently, we reported the ameliorative role of 6-gingerol-rich fraction from Zingiber officinale (Ginger, GRF) on the...

Melatonin administration lowers biomarkers of oxidative stress and cardio-metabolic risk in type 2 diabetic patients with coronary heart disease: A randomized, double-blind, placebo-controlled trial.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND & AIMS: Melatonin may benefit diabetic people with coronary heart disease (CHD) through its beneficial effects on biomarkers of oxidative stress and cardio-metabolic risk. This investigation evaluated the effects of melatonin administratio...

Deep machine learning-assisted MOF@COF fluorescence/colorimetric dual-mode intelligent ratiometric sensing platform for sensitive glutathione detection.

Talanta
Glutathione (GSH) levels have been linked to aging and the pathogenesis of various diseases, highlighting the necessity for the development of sensitive analytical methods for GSH to facilitate disease diagnosis and treatment. In this study, we synth...

Machine Learning-Enabled Time-Resolved Nanozyme-Encoded Recognition of Endogenous Mercaptans for Disease Diagnosis.

Analytical chemistry
With their important role in regulating intracellular redox balance and maintaining cell homeostasis, endogenous mercaptans are recognized as biomarkers of many diseases in clinical practice, and thus establishing efficient yet simple methods to dist...

Machine learning-assisted surface-enhanced raman spectroscopy for the rapid determination of the glutathione redox ratio.

The Analyst
Rapid and accurate detection of glutathione in its reduced (GSH) and oxidized (GSSG) forms is essential for monitoring oxidative stress in biological systems. Oxidative stress is a key indicator of various diseases, and glutathione plays a vital role...