AIMC Topic: Graft Rejection
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Diagnosis of T-cell-mediated kidney rejection in formalin-fixed, paraffin-embedded tissues using RNA-Seq-based machine learning algorithms.
Human pathology
Oct 6, 2018
Molecular diagnosis is being increasingly used in transplant pathology to render more objective and quantitative determinations that also provide mechanistic and prognostic insights. This study performed RNA-Seq on biopsies from kidneys with stable f...
A dynamic model for predicting graft function in kidney recipients' upcoming follow up visits: A clinical application of artificial neural network.
International journal of medical informatics
Sep 12, 2018
BACKGROUND: Predicting the function of transplanted kidneys would help clinicians in individualized medical interventions. We aimed to develop and validate a predictive tool for a future value of estimated glomerular filtration rate (eGFR) at upcomin...
Efficacy of Platelet-Rich Plasma on Fat Grafts in the Repair of Tympanic Membrane Perforations: An Experimental Study.
The journal of international advanced otology
Dec 14, 2017
OBJECTIVE: We investigated the use of autologous platelet-rich plasma (PRP) to improve the success rate of fat graft myringoplasty in perforated tympanic membranes of rats.
Effect of the vascularized bone components on the survival of vascularized composite allografts.
The Journal of surgical research
Apr 6, 2017
BACKGROUND: Vascularized composite allograft (VCA), such as hand and face allograft, contains a vascularized bone component that may provide an immunologic benefit and induce tolerance for the simultaneous inclusion of marrow cells and a marrow micro...
High soluble CD30 levels and associated anti-HLA antibodies in patients with failed renal allografts.
The International journal of artificial organs
Dec 26, 2016
INTRODUCTION: Serum soluble CD30 (sCD30), a 120-kD glycoprotein that belongs to the tumor necrosis factor receptor family, has been suggested as a marker of rejection in kidney transplant patients. The aim of this study was to evaluate the relationsh...
Re: Robotic Trans-Abdominal Transplant Nephrectomy for a Failed Renal Allograft.
The Journal of urology
Apr 8, 2015
Deep learning-based histopathologic segmentation of peritubular capillaries in kidney transplant biopsies.
Computers in biology and medicine
Jul 1, 2025
BACKGROUND: Assessing the extent of inflammation in peritubular capillaries (PTCs) is important for diagnosing antibody-mediated rejection in kidney transplant biopsies. However, this assessment is time-consuming and suffers from interobserver variab...
Artificial intelligence-enhanced interpretation of kidney transplant biopsy: focus on rejection.
Current opinion in organ transplantation
Jun 1, 2025
PURPOSE OF REVIEW: The objective of this review is to provide an update on the application of artificial intelligence (AI) for the histological interpretation of kidney transplant biopsies.
GraftIQ: Hybrid multi-class neural network integrating clinical insight for multi-outcome prediction in liver transplant recipients.
Nature communications
May 28, 2025
Liver transplant recipients (LTRs) are at risk of graft injury, leading to cirrhosis and reduced survival. Liver biopsy, the diagnostic gold standard, is invasive and risky. We developed a hybrid multi-class neural network (NN) model, 'GraftIQ,' inte...
On the Harmonisation of Time Series Data for the Optimisation of Machine Learning Using the Example of Rejection Prediction After Kidney Transplantation.
Studies in health technology and informatics
May 15, 2025
A significant risk following a kidney transplantation is graft loss. The Screen Reject Project has developed a Clinical Data Warehouse (CDWH) as a foundation for a clinical decision support system designed to improve the diagnosis of graft rejections...
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