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Head and Neck Neoplasms

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Knowledge-Based Tradeoff Hyperplanes for Head and Neck Treatment Planning.

International journal of radiation oncology, biology, physics
PURPOSE: To develop a tradeoff hyperplane model to facilitate tradeoff decision-making before inverse planning.

Automatic classification of dental artifact status for efficient image veracity checks: effects of image resolution and convolutional neural network depth.

Physics in medicine and biology
Enabling automated pipelines, image analysis and big data methodology in cancer clinics requires thorough understanding of the data. Automated quality assurance steps could improve the efficiency and robustness of these methods by verifying possible ...

Multimodality image registration in the head-and-neck using a deep learning-derived synthetic CT as a bridge.

Medical physics
PURPOSE: To develop and demonstrate the efficacy of a novel head-and-neck multimodality image registration technique using deep-learning-based cross-modality synthesis.

Multi-Institutional Validation of Deep Learning for Pretreatment Identification of Extranodal Extension in Head and Neck Squamous Cell Carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
PURPOSE: Extranodal extension (ENE) is a well-established poor prognosticator and an indication for adjuvant treatment escalation in patients with head and neck squamous cell carcinoma (HNSCC). Identification of ENE on pretreatment imaging represents...

Comparing deep learning-based auto-segmentation of organs at risk and clinical target volumes to expert inter-observer variability in radiotherapy planning.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND: Deep learning-based auto-segmented contours (DC) aim to alleviate labour intensive contouring of organs at risk (OAR) and clinical target volumes (CTV). Most previous DC validation studies have a limited number of expert observers for com...

Improving automatic delineation for head and neck organs at risk by Deep Learning Contouring.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
INTRODUCTION: Adequate head and neck (HN) organ-at-risk (OAR) delineation is crucial for HN radiotherapy and for investigating the relationships between radiation dose to OARs and radiation-induced side effects. The automatic contouring algorithms th...

Machine learning methods applied to audit of surgical outcomes after treatment for cancer of the head and neck.

The British journal of oral & maxillofacial surgery
Most surgical specialties have attempted to address concerns about unfair comparison of outcomes by "risk-adjusting" data to benchmark specialty-specific outcomes that are indicative of the quality of care. We are building on previous work in head an...

Automated 4π radiotherapy treatment planning with evolving knowledge-base.

Medical physics
PURPOSE: Non-coplanar 4π radiotherapy generalizes intensity modulated radiation therapy (IMRT) to automate beam geometry selection but requires complicated hyperparameter tuning to attain superior plan quality, which can be tedious and inconsistent. ...

Dosimetric evaluation of synthetic CT for head and neck radiotherapy generated by a patch-based three-dimensional convolutional neural network.

Medical physics
PURPOSE: To develop and evaluate a patch-based convolutional neural network (CNN) to generate synthetic computed tomography (sCT) images for magnetic resonance (MR)-only workflow for radiotherapy of head and neck tumors. A patch-based deep learning m...