Studies in health technology and informatics
29295359
We have used deep neural networks (DNNs) to generate clinical opinions from general blood test results. DNNs have overfitting problem in general. We believe the complex structure of DNN and insufficient data to be the major reasons of overfitting in ...
BACKGROUND: Acute pancreatitis (AP) can induce portosplenomesenteric vein thrombosis (PVT), which may generate higher morbidity and mortality. However current diagnostic modalities for PVT are still controversial. In recent decades, artificial neural...
Peripheral Blood Smear analysis plays a vital role in diagnosis of many diseases such as leukemia, anemia, malaria, lymphoma and infections. Unusual variations in color, shape and size of blood cells indicate abnormal condition. We used a total of 11...
Machine learning and data mining approaches are being successfully applied to different fields of life sciences for the past 20 years. Medicine is one of the most suitable application domains for these techniques since they help model diagnostic info...
Acute Leukemia is a life-threatening disease common both in children and adults that can lead to death if left untreated. Acute Lymphoblastic Leukemia (ALL) spreads out in children's bodies rapidly and takes the life within a few weeks. To diagnose A...
The Journal of antimicrobial chemotherapy
30590545
BACKGROUND: Infection diagnosis can be challenging, relying on clinical judgement and non-specific markers of infection. We evaluated a supervised machine learning (SML) algorithm for diagnosing bacterial infection using routinely available blood par...
Journal of chemical information and modeling
31609612
Tuberculosis remains one of the deadliest infectious diseases worldwide. Only 5-15% of people infected with develop active TB disease (ATB), while others remain latently infected (LTBI) during their lifetime, which has a completely different clinica...
Routine blood test results are assumed to contain much more information than is usually recognised even by the most experienced clinicians. Using routine blood tests from 15,176 neurological patients we built a machine learning predictive model for t...