AIMC Topic: Humans

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Predicting 30-day and 1-year mortality in heart failure with preserved ejection fraction (HFpEF).

PloS one
OBJECTIVES: To develop and compare prediction models for 30-day and 1-year mortality in Heart failure with preserved ejection fraction (HFpEF) using EHR data, utilizing both traditional and machine learning (ML) techniques.

Towards an optimized paradigm: generative adversarial networks and 3D modeling in landscape design and generation.

PloS one
Virtual reality (VR) integrates technologies like computer graphics, artificial intelligence, and multi-sensor systems, creating transformative tools for designers and users. This study proposes a novel urban landscape design method using 3D laser sc...

MRI-based 2.5D deep learning and radiomics effectively predicted microvascular invasion and Ki-67 expression in hepatocellular carcinoma.

PloS one
OBJECTIVE: To develop and validate an integrated 2.5D deep learning (DL) and Radiomics model using gadoxetic acid-enhanced MRI hepatobiliary phase (HBP) images combined with clinical features for preoperative prediction of microvascular invasion (MVI...

Recognition method of bridge apparent defects based on image processing and improved convolutional neural networks.

PloS one
As an important transportation hub, the detection of appearance defects in bridges has been characterized by low accuracy and low efficiency. To address this problem, the study proposes a bridge appearance defect recognition model based on image proc...

From wastewater to epidemiological insights: A systematic review of modeling strategies for infectious disease surveillance.

Water research
Wastewater-based epidemiology (WBE) has emerged as a promising complementary tool in infectious diseases surveillance systems, offering real-time insights into the disease dynamics across various spatial coverage. By leveraging wastewater data, a wid...

Predictive surveillance and diagnosis of COVID-19: An integrative machine learning and wastewater multi-omics approach.

Water research
COVID-19 has had major global impacts, highlighting the importance of robust predictive surveillance and diagnostic systems to ensure effective public health responses. Traditional surveillance methods based on passive case counting and diagnostic te...

Genetic and Genomic Testing in Cardiovascular Disease: A Policy Statement From the American Heart Association.

Circulation
The rapid advancement of genomic and precision medicine has expanded the role of genetics and genomics in the diagnosis, risk stratification, and management of cardiovascular diseases. With the decreasing cost and increasing accessibility of genetic ...

Gender-specific effectiveness of dialectic-behavioral therapy for patients with complex post-traumatic stress disorder (DBT-PTSD) - results of an observational single center study.

European journal of psychotraumatology
Complex post-traumatic stress disorder (cPTSD) was recently included in the ICD-11, extending the PTSD symptom profile to encompass disturbances in self-organization (DSO). Trauma-focused Dialectical Behavior Therapy (DBT-PTSD) is an effective psych...

Selectivity Approaches in Therapeutic Antibody Design.

Journal of medicinal chemistry
Protein therapeutics, particularly antibody-based therapies, have emerged as a cornerstone in modern disease treatment, offering key advantages over small molecules, including superior target specificity, longer half-life, and expanded target accessi...

DART Predictor: A Multi-Label Attention Model for High-Throughput Screening of Chemicals with Developmental and Reproductive Toxicity (DART).

Environmental science & technology
Chemicals with developmental and reproductive toxicity (DART) pose significant risks to human health, particularly exposure during critical windows of embryonic and fetal development. Therefore, rapid and accurate identification of DART chemicals is ...