AIMC Topic: Humans

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Integrating bioinformatics and machine learning methods to analyze diagnostic biomarkers for HBV-induced hepatocellular carcinoma.

Diagnostic pathology
Hepatocellular carcinoma (HCC) is a malignant tumor. It is estimated that approximately 50-80% of HCC cases worldwide are caused by hepatitis b virus (HBV) infection, and other pathogenic factors have been shown to promote the development of HCC when...

Can supervised deep learning architecture outperform autoencoders in building propensity score models for matching?

BMC medical research methodology
PURPOSE: Propensity score matching is vital in epidemiological studies using observational data, yet its estimates relies on correct model-specification. This study assesses supervised deep learning models and unsupervised autoencoders for propensity...

Interactive molecular causal networks of hypertension using a fast machine learning algorithm MRdualPC.

BMC medical research methodology
BACKGROUND: Understanding the complex interactions between genes and their causal effects on diseases is crucial for developing targeted treatments and gaining insight into biological mechanisms. However, the analysis of molecular networks, especiall...

Enhanced skin cancer diagnosis using optimized CNN architecture and checkpoints for automated dermatological lesion classification.

BMC medical imaging
Skin cancer stands as one of the foremost challenges in oncology, with its early detection being crucial for successful treatment outcomes. Traditional diagnostic methods depend on dermatologist expertise, creating a need for more reliable, automated...

Differentially localized protein identification for breast cancer based on deep learning in immunohistochemical images.

Communications biology
The mislocalization of proteins leads to breast cancer, one of the world's most prevalent cancers, which can be identified from immunohistochemical images. Here, based on the deep learning framework, location prediction models were constructed using ...

Identifying diseases symptoms and general rules using supervised and unsupervised machine learning.

Scientific reports
The symptoms of diseases can vary among individuals and may remain undetected in the early stages. Detecting these symptoms is crucial in the initial stage to effectively manage and treat cases of varying severity. Machine learning has made major adv...

Machine learning in diagnostic support in medical emergency departments.

Scientific reports
Diagnosing patients in the medical emergency department is complex and this is expected to increase in many countries due to an ageing population. In this study we investigate the feasibility of training machine learning algorithms to assist physicia...

Deep learning predicts the 1-year prognosis of pancreatic cancer patients using positive peritoneal washing cytology.

Scientific reports
Peritoneal washing cytology (CY) in patients with pancreatic cancer is mainly used for staging; however, it may also be used to evaluate the intraperitoneal status to predict a more accurate prognosis. Here, we investigated the potential of deep lear...

Phenotype prediction using biologically interpretable neural networks on multi-cohort multi-omics data.

NPJ systems biology and applications
Integrating multi-omics data into predictive models has the potential to enhance accuracy, which is essential for precision medicine. In this study, we developed interpretable predictive models for multi-omics data by employing neural networks inform...

Identifying sex from pharyngeal images using deep learning algorithm.

Scientific reports
The pharynx is one of the few areas in the body where blood vessels and immune tissues can readily be observed from outside the body non-invasively. Although prior studies have found that sex could be identified from retinal images using artificial i...