The success of prime editing depends on the prime editing guide RNA (pegRNA) design and target locus. Here, we developed machine learning models that reliably predict prime editing efficiency. PRIDICT2.0 assesses the performance of pegRNAs for all ed...
Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society
Jun 21, 2024
OBJECTIVES: Colonoscopy (CS) is an important screening method for the early detection and removal of precancerous lesions. The stool state during bowel preparation (BP) should be properly evaluated to perform CS with sufficient quality. This study ai...
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
Jun 21, 2024
Psychiatric disorders have a complex biological underpinning likely involving an interplay of genetic and environmental risk contributions. Substantial efforts are being made to use artificial intelligence approaches to integrate features within and ...
BACKGROUND: The IDENTIFY study developed a model to predict urinary tract cancer using patient characteristics from a large multicentre, international cohort of patients referred with haematuria. In addition to calculating an individual's cancer risk...
OBJECTIVES: This study investigated the diagnostic performance of dual-energy computed tomography (CT) and deep learning for the preoperative classification of equivocal lymph nodes (LNs) on CT images in thyroid cancer patients.
RATIONALE AND OBJECTIVES: To assess a deep learning application (DLA) for acute ischemic stroke (AIS) detection on brain magnetic resonance imaging (MRI) in the emergency room (ER) and the effect of T2-weighted imaging (T2WI) on its performance.
RATIONALE AND OBJECTIVES: The objective of this study was to evaluate the effectiveness of a pilot artificial intelligence (AI) certificate program in aiding radiology trainees to develop an understanding of the evolving role and application of artif...
European journal of nuclear medicine and molecular imaging
Jun 21, 2024
INTRODUCTION: Prosthetic valve endocarditis (PVE) is a serious complication of prosthetic valve implantation, with an estimated yearly incidence of at least 0.4-1.0%. The Duke criteria and subsequent modifications have been developed as a diagnostic ...
Short-term exposure to ground-level ozone (O) poses significant health risks, particularly respiratory and cardiovascular diseases, and mortality. This study addresses the pressing need for accurate O forecasting to mitigate these risks, focusing on ...
Journal of evaluation in clinical practice
Jun 21, 2024
RATIONALE: Clinical abbreviations pose a challenge for clinical decision support systems due to their ambiguity. Additionally, clinical datasets often suffer from class imbalance, hindering the classification of such data. This imbalance leads to cla...
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