AIMC Topic: Humans

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RAPHIA: A deep learning pipeline for the registration of MRI and whole-mount histopathology images of the prostate.

Computers in biology and medicine
Image registration can map the ground truth extent of prostate cancer from histopathology images onto MRI, facilitating the development of machine learning methods for early prostate cancer detection. Here, we present RAdiology PatHology Image Alignm...

[Development of an artificial intelligence system to improve cancer clinical trial eligibility screening].

Bulletin du cancer
INTRODUCTION: The recruitment step of all clinical trials is time consuming, harsh and generate extra costs. Artificial intelligence tools could improve recruitment in order to shorten inclusion phase. The objective was to assess the performance of a...

A matching-based machine learning approach to estimating optimal dynamic treatment regimes with time-to-event outcomes.

Statistical methods in medical research
Observational data (e.g. electronic health records) has become increasingly important in evidence-based research on dynamic treatment regimes, which tailor treatments over time to patients based on their characteristics and evolving clinical history....

Development of a Machine Learning Model to Predict the Use of Surgery in Patients With Rheumatoid Arthritis.

Arthritis care & research
OBJECTIVE: One in five patients with rheumatoid arthritis (RA) rely on surgery to restore joint function. However, variable response to disease-modifying antirheumatic drugs (DMARDs) complicates surgical planning, and it is difficult to predict which...

Bimodal Intelligent Electronic Skin Based on Proximity and Tactile Interaction for Pressure and Configuration Perception.

ACS sensors
The flexible bimodal e-skin exhibits significant promise for integration into the next iteration of human-computer interactions, owing to the integration of tactile and proximity perception. However, those challenges, such as low tactile sensitivity,...

Kinetic Ensemble of Tau Protein through the Markov State Model and Deep Learning Analysis.

Journal of chemical theory and computation
The ordered assembly of Tau protein into filaments characterizes Alzheimer's and other neurodegenerative diseases, and thus, stabilization of Tau protein is a promising avenue for tauopathies therapy. To dissect the underlying aggregation mechanisms ...

Artificial intelligence tools for optimising recruitment and retention in clinical trials: a scoping review protocol.

BMJ open
INTRODUCTION: In recent years, the influence of artificial intelligence technology on clinical trials has been steadily increasing. It has brought about significant improvements in the efficiency and cost reduction of clinical trials. The objective o...

Inter-reviewer reliability of human literature reviewing and implications for the introduction of machine-assisted systematic reviews: a mixed-methods review.

BMJ open
OBJECTIVES: Our main objective is to assess the inter-reviewer reliability (IRR) reported in published systematic literature reviews (SLRs). Our secondary objective is to determine the expected IRR by authors of SLRs for both human and machine-assist...

Comparing a pre-defined versus deep learning approach for extracting brain atrophy patterns to predict cognitive decline due to Alzheimer's disease in patients with mild cognitive symptoms.

Alzheimer's research & therapy
BACKGROUND: Predicting future Alzheimer's disease (AD)-related cognitive decline among individuals with subjective cognitive decline (SCD) or mild cognitive impairment (MCI) is an important task for healthcare. Structural brain imaging as measured by...

DANCE: a deep learning library and benchmark platform for single-cell analysis.

Genome biology
DANCE is the first standard, generic, and extensible benchmark platform for accessing and evaluating computational methods across the spectrum of benchmark datasets for numerous single-cell analysis tasks. Currently, DANCE supports 3 modules and 8 po...