This research employed integrated machine learning and bioinformatics approaches to identify umami-enhancing peptides from Flammulina filiformis, elucidate their mechanisms of umami augmentation, and validate their efficacy through sensory evaluation...
Recently, technology has evolved significantly in the rehabilitation process for neurological disorders and neurodegenerative diseases, focusing on neuroplasticity. Neuroplasticity, as a fundamental base of brain rehabilitation, is the change in the ...
Neurological disorders continue to be a leading global health challenge, with the blood-brain barrier (BBB) presenting considerable obstacles to effective drug delivery for central nervous system (CNS) therapies. Accurately predicting BBB permeabilit...
Groundwater is threatened by climate change and human activities, with depletion and contamination emerging as critical risks, necessitating the development of models to estimate its response to changes. Artificial intelligence (AI) is gaining increa...
Accurate and accessible molecular diagnostics are critical for early disease detection, infection control, and personalized medicine. Digital nucleic acid testing offers absolute quantification by isolating individual amplification events into discre...
BACKGROUND: Amyloid PET/CT is essential for quantifying amyloid-beta (Aβ) deposition in Alzheimer's disease (AD), with the Centiloid (CL) scale standardizing measurements across imaging centers. However, MRI-based CL pipelines face challenges: high c...
BACKGROUND: Ulcerative colitis (UC) is a chronic nonspecific inflammatory intestinal disease affecting the mucosa and submucosa, characterized by continuous and diffuse active inflammation. However, its underlying pathogenesis remains unclear.
INTRODUCTION: Quantification of amyloid plaques (A), neurofibrillary tangles (T), and neurodegeneration (N) using PET and MRI is critical for Alzheimer's disease (AD) diagnosis and prognosis. Existing pipelines face limitations regarding processing t...
BACKGROUND: The combination of healthcare and artificial intelligence (AI) has profoundly changed the course of certain areas of nursing. Postgraduate nursing students, as key contributors to the discipline's development, warrant investigation regard...
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