OBJECTIVE: The purpose of this study was: To test whether machine learning classifiers for transition zone (TZ) and peripheral zone (PZ) can correctly classify prostate tumors into those with/without a Gleason 4 component, and to compare the performa...
Molecular biological findings indicate that affective disorders are associated with processes akin to accelerated aging of the brain. The use of the BrainAGE (brain age estimation gap) framework allows machine-learning based detection of a gap betwee...
PURPOSE: Dilated cardiomyopathy (DCM) is a common form of cardiomyopathy and it is associated with poor outcomes. A poor prognosis of DCM patients with low ejection fraction has been noted in the short-term follow-up. Machine learning (ML) could aid ...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 11, 2019
INTRODUCTION: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia.
PURPOSE: Quantification of carotid plaques has been shown to be important for assessing as well as monitoring the progression and regression of carotid atherosclerosis. Various metrics have been proposed and methods of measurements ranging from manua...
International journal of molecular sciences
Jun 11, 2019
During the past decade, due to the number of proteins in PDB database being increased gradually, traditional methods cannot better understand the function of newly discovered enzymes in chemical reactions. Computational models and protein feature rep...
Modeling in-vivo protein-DNA binding is not only fundamental for further understanding of the regulatory mechanisms, but also a challenging task in computational biology. Deep-learning based methods have succeed in modeling in-vivo protein-DNA bindin...
We applied deep convolutional neural networks (CNNs) to detect periodontal bone loss (PBL) on panoramic dental radiographs. We synthesized a set of 2001 image segments from panoramic radiographs. Our reference test was the measured % of PBL. A deep f...
Journal of neuroengineering and rehabilitation
Jun 11, 2019
BACKGROUND: Falls in the elderly constitute a major health issue associated to population ageing. Current clinical tests evaluating fall risk mostly consist in assessing balance abilities. The devices used for these tests can be expensive or inconven...
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