AIMC Topic: Humans

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Deep Learning Predicts Lung Cancer Treatment Response from Serial Medical Imaging.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Tumors are continuously evolving biological systems, and medical imaging is uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking lesions over space and time may be trivial, the development of clinicall...

Machine-Learning-Based Predictor of Human-Bacteria Protein-Protein Interactions by Incorporating Comprehensive Host-Network Properties.

Journal of proteome research
The large-scale identification of protein-protein interactions (PPIs) between humans and bacteria remains a crucial step in systematically understanding the underlying molecular mechanisms of bacterial infection. Computational prediction approaches a...

mACPpred: A Support Vector Machine-Based Meta-Predictor for Identification of Anticancer Peptides.

International journal of molecular sciences
Anticancer peptides (ACPs) are promising therapeutic agents for targeting and killing cancer cells. The accurate prediction of ACPs from given peptide sequences remains as an open problem in the field of immunoinformatics. Recently, machine learning ...

A quantitative SVM approach potentially improves the accuracy of magnetic resonance spectroscopy in the preoperative evaluation of the grades of diffuse gliomas.

NeuroImage. Clinical
OBJECTIVES: To investigate the association between proton magnetic resonance spectroscopy (H-MRS) metabolic features and the grade of gliomas, and to establish a machine-learning model to predict the glioma grade.

Predicting childhood obesity using electronic health records and publicly available data.

PloS one
BACKGROUND: Because of the strong link between childhood obesity and adulthood obesity comorbidities, and the difficulty in decreasing body mass index (BMI) later in life, effective strategies are needed to address this condition in early childhood. ...

Artificial intelligence in medical education.

Medical teacher
Artificial intelligence (AI) is a growing phenomenon, and will soon facilitate wide-scale changes in many professions, including medical education. In order for medical educators to be properly prepared for AI, they will need to have at least a funda...

Novel pediatric-automated respiratory score using physiologic data and machine learning in asthma.

Pediatric pulmonology
OBJECTIVES: Manual clinical scoring systems are the current standard used for acute asthma clinical care pathways. No automated system exists that assesses disease severity, time course, and treatment impact in pediatric acute severe asthma exacerbat...

In silico prediction of drug-induced rhabdomyolysis with machine-learning models and structural alerts.

Journal of applied toxicology : JAT
Drug-induced rhabdomyolysis (DIR) is a serious adverse reaction and can be fatal. In the present study, we focused on the modeling and understanding of the molecular basis of DIR of small molecule drugs. A series of machine-learning models were devel...

Advanced atherosclerosis imaging by CT: Radiomics, machine learning and deep learning.

Journal of cardiovascular computed tomography
In the last decade, technical advances in the field of medical imaging significantly improved and broadened the application of coronary CT angiography (CCTA) for the non-invasive assessment of coronary artery disease. Recently, similar breakthroughs ...