Patient classification has widespread biomedical and clinical applications, including diagnosis, prognosis, and treatment response prediction. A clinically useful prediction algorithm should be accurate, generalizable, be able to integrate diverse da...
BMC medical informatics and decision making
Mar 14, 2019
BACKGROUND: Social isolation is an important social determinant that impacts health outcomes and mortality among patients. The National Academy of Medicine recently recommended that social isolation be documented in electronic health records (EHR). H...
BACKGROUND: Topologically associating domains (TADs) are considered the structural and functional units of the genome. However, there is a lack of an integrated resource for TADs in the literature where researchers can obtain family classifications a...
Chronic low back pain (cLBP) is associated with widespread functional and structural changes in the brain. This study aims to investigate the resting state functional connectivity (rsFC) changes of visual networks in cLBP patients and the feasibility...
IEEE transactions on bio-medical engineering
Mar 13, 2019
OBJECTIVE: Multi-modal functional magnetic resonance imaging has been widely used for brain research. Conventional data-fusion methods cannot capture complex relationship (e.g., nonlinear predictive relationship) between multiple data. This paper aim...
Machine-learning methods can assist with the medical decision-making processes at the both the clinical and diagnostic levels. In this article, we first review historical milestones and specific applications of computer-based medical decision support...
This study aimed to identify the optimal radiomic machine-learning classifier for differentiating glioblastoma (GBM) from solitary brain metastases (MET) preoperatively. Four hundred and twelve patients with solitary brain tumors (242 GBM and 170 sol...
Computer methods and programs in biomedicine
Mar 13, 2019
BACKGROUND AND OBJECTIVES: Parkinson's disease is a neurological disorder that affects the motor system producing lack of coordination, resting tremor, and rigidity. Impairments in handwriting are among the main symptoms of the disease. Handwriting a...
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