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Showing 68251 to 68260 of 95995 articles
PAIN(S) relievers for medicinal chemists: how computational methods can assist in hit evaluation.
Future medicinal chemistry
Jun 29, 2018
Protein Secondary Structure Prediction Based on Data Partition and Semi-Random Subspace Method.
Scientific reports
Jun 29, 2018
Protein secondary structure prediction is one of the most important and challenging problems in bioinformatics. Machine learning techniques have been applied to solve the problem and have gained substantial success in this research area. However ther...
Gait Estimation from Anatomical Foot Parameters Measured by a Foot Feature Measurement System using a Deep Neural Network Model.
Scientific reports
Jun 29, 2018
An accurate and credible measurement of human gait is essential in multiple areas of medical science and rehabilitation. Yet, the methods currently available are not only arduous but also costly. Researchers who investigated the relationship between ...
Bioimpedance and New-Onset Heart Failure: A Longitudinal Study of >500 000 Individuals From the General Population.
Journal of the American Heart Association
Jun 29, 2018
BACKGROUND: Heart failure constitutes a high burden on patients and society, but although lifetime risk is high, it is difficult to predict without costly or invasive testing. We aimed to establish new risk factors of heart failure, which potentially...
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Augmenting Qualitative Text Analysis with Natural Language Processing: Methodological Study.
Journal of medical Internet research
Jun 29, 2018
BACKGROUND: Qualitative research methods are increasingly being used across disciplines because of their ability to help investigators understand the perspectives of participants in their own words. However, qualitative analysis is a laborious and re...
Introducing chaos behavior to kernel relevance vector machine (RVM) for four-class EEG classification.
PloS one
Jun 29, 2018
This paper addresses a chaos kernel function for the relevance vector machine (RVM) in EEG signal classification, which is an important component of Brain-Computer Interface (BCI). The novel kernel function has evolved from a chaotic system, which is...
Towards better prediction of Mycobacterium tuberculosis lineages from MIRU-VNTR data.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
Jun 28, 2018
The determination of lineages from strain-based molecular genotyping information is an important problem in tuberculosis. Mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) typing is a commonly used molecular genotyp...
Detecting intertrochanteric hip fractures with orthopedist-level accuracy using a deep convolutional neural network.
Skeletal radiology
Jun 28, 2018
OBJECTIVE: To compare performances in diagnosing intertrochanteric hip fractures from proximal femoral radiographs between a convolutional neural network and orthopedic surgeons.
Recent applications of machine learning in medicinal chemistry.
Bioorganic & medicinal chemistry letters
Jun 28, 2018
In recent decades, artificial intelligence and machine learning have played a significant role in increasing the efficiency of processes across a wide spectrum of industries. When it comes to the pharmaceutical and biotechnology sectors, numerous too...
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Machine learning models to predict the progression from early to late stages of papillary renal cell carcinoma.
Computers in biology and medicine
Jun 28, 2018
Papillary Renal Cell Carcinoma (PRCC) is a heterogeneous disease with variations in disease progression and clinical outcomes. The advent of next generation sequencing techniques (NGS) has generated data from patients that can be analysed to develop ...
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