Humans

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Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning.

BMC research notes Jan 27, 2018
OBJECTIVE: Use of opioids for pain management has increased over the past decade; however, inadequate analgesic response is common. Genetic variability may be related to opioid efficacy, but due to the many possible combinations and variables, statis...
Receptors, Opioid, delta Cancer Pain Receptors, Opioid, mu Catechol O-Methyltransferase Middle Aged Polymorphism, Single Nucleotide Genotype Support Vector Machine Dose-Response Relationship, Drug Analgesics, Opioid Morphine Gene Frequency Humans Female Aged Male
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Artificial intelligence, physiological genomics, and precision medicine.

Physiological genomics Jan 26, 2018
Big data are a major driver in the development of precision medicine. Efficient analysis methods are needed to transform big data into clinically-actionable knowledge. To accomplish this, many researchers are turning toward machine learning (ML), an ...
Artificial Intelligence Machine Learning Algorithms Precision Medicine Humans Genomics
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Decoding diagnosis and lifetime consumption in alcohol dependence from grey-matter pattern information.

Acta psychiatrica Scandinavica Jan 26, 2018
OBJECTIVE: We investigated the potential of computer-based models to decode diagnosis and lifetime consumption in alcohol dependence (AD) from grey-matter pattern information. As machine-learning approaches to psychiatric neuroimaging have recently c...
(1)
Gray Matter Alcohol Drinking Humans Cerebral Cortex Atrophy Adult Magnetic Resonance Imaging Male Middle Aged Image Processing, Computer-Assisted Machine Learning Female Aged Young Adult Image Interpretation, Computer-Assisted Alcoholism
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A Shared Vision for Machine Learning in Neuroscience.

The Journal of neuroscience : the official journal of the Society for Neuroscience Jan 26, 2018
With ever-increasing advancements in technology, neuroscientists are able to collect data in greater volumes and with finer resolution. The bottleneck in understanding how the brain works is consequently shifting away from the amount and type of data...
Connectome Humans Reproducibility of Results Machine Learning Neurosciences Animals Brain Big Data Information Dissemination
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Multicentre validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU.

BMJ open Jan 26, 2018
OBJECTIVES: We validate a machine learning-based sepsis-prediction algorithm () for the detection and prediction of three sepsis-related gold standards, using only six vital signs. We evaluate robustness to missing data, customisation to site-specifi...
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Humans Machine Learning Algorithms Databases, Factual Prognosis San Francisco Retrospective Studies Boston Intensive Care Units Sepsis Patients' Rooms Female Adolescent Hospital Mortality Male ROC Curve Middle Aged Shock, Septic Severity of Illness Index Aged Area Under Curve Length of Stay Young Adult Emergency Service, Hospital Adult Vital Signs
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Predicting non-melanoma skin cancer via a multi-parameterized artificial neural network.

Scientific reports Jan 26, 2018
Ultraviolet radiation (UVR) exposure and family history are major associated risk factors for the development of non-melanoma skin cancer (NMSC). The objective of this study was to develop and validate a multi-parameterized artificial neural network ...
Humans Neural Networks, Computer Decision Support Techniques Middle Aged ROC Curve Diagnostic Tests, Routine Early Diagnosis Female Skin Neoplasms Sensitivity and Specificity Male
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Drug drug interaction extraction from the literature using a recursive neural network.

PloS one Jan 26, 2018
Detecting drug-drug interactions (DDI) is important because information on DDIs can help prevent adverse effects from drug combinations. Since there are many new DDI-related papers published in the biomedical domain, manually extracting DDI informati...
Drug-Related Side Effects and Adverse Reactions Data Mining Pharmacokinetics Humans Support Vector Machine Neural Networks, Computer Natural Language Processing Publications Drug Interactions
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Higher Serum Endocan Level Is Associated with Alzheimer Disease.

Dementia and geriatric cognitive disorders Jan 26, 2018
BACKGROUND: The novel molecule endocan, which is released by endothelium and is regulated by proangiogenic and proinflammatory cytokines, may have a role in the pathophysiology of Alzheimer disease (AD). The aim of this study was to evaluate the rela...
ROC Curve Humans Proteoglycans Aged Reference Values Biomarkers Neoplasm Proteins Alzheimer Disease Aged, 80 and over Female Neuropsychological Tests Geriatric Assessment Male Cognitive Dysfunction
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Classification of Pre-Clinical Seizure States Using Scalp EEG Cross-Frequency Coupling Features.

IEEE transactions on bio-medical engineering Jan 25, 2018
OBJECTIVE: This work proposes a machine-learning based system for a scalp EEG that flags an alarm in advance of a clinical seizure onset.
Seizures Signal Processing, Computer-Assisted Scalp Machine Learning ROC Curve Electroencephalography Humans
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Content Based Image Retrieval by Using Color Descriptor and Discrete Wavelet Transform.

Journal of medical systems Jan 25, 2018
Due to recent development in technology, the complexity of multimedia is significantly increased and the retrieval of similar multimedia content is a open research problem. Content-Based Image Retrieval (CBIR) is a process that provides a framework f...
Image Interpretation, Computer-Assisted Information Storage and Retrieval Pattern Recognition, Automated Wavelet Analysis Humans Artificial Intelligence Algorithms
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