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Construction of environmental risk score beyond standard linear models using machine learning methods: application to metal mixtures, oxidative stress and cardiovascular disease in NHANES.

Environmental health : a global access science source
BACKGROUND: There is growing concern of health effects of exposure to pollutant mixtures. We initially proposed an Environmental Risk Score (ERS) as a summary measure to examine the risk of exposure to multi-pollutants in epidemiologic research consi...

Anticipatory detection of turning in humans for intuitive control of robotic mobility assistance.

Bioinspiration & biomimetics
Many wearable lower-limb robots for walking assistance have been developed in recent years. However, it remains unclear how they can be commanded in an intuitive and efficient way by their user. In particular, providing robotic assistance to neurolog...

Distant Supervision with Transductive Learning for Adverse Drug Reaction Identification from Electronic Medical Records.

Journal of healthcare engineering
Information extraction and knowledge discovery regarding adverse drug reaction (ADR) from large-scale clinical texts are very useful and needy processes. Two major difficulties of this task are the lack of domain experts for labeling examples and int...

Meaningless comparisons lead to false optimism in medical machine learning.

PloS one
A new trend in medicine is the use of algorithms to analyze big datasets, e.g. using everything your phone measures about you for diagnostics or monitoring. However, these algorithms are commonly compared against weak baselines, which may contribute ...

Localization of Origins of Premature Ventricular Contraction by Means of Convolutional Neural Network From 12-Lead ECG.

IEEE transactions on bio-medical engineering
OBJECTIVE: This paper proposes a novel method to localize origins of premature ventricular contractions (PVCs) from 12-lead electrocardiography (ECG) using convolutional neural network (CNN) and a realistic computer heart model.
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Prediction of lung cancer patient survival via supervised machine learning classification techniques.

International journal of medical informatics
Outcomes for cancer patients have been previously estimated by applying various machine learning techniques to large datasets such as the Surveillance, Epidemiology, and End Results (SEER) program database. In particular for lung cancer, it is not we...

Relating dynamic brain states to dynamic machine states: Human and machine solutions to the speech recognition problem.

PLoS computational biology
There is widespread interest in the relationship between the neurobiological systems supporting human cognition and emerging computational systems capable of emulating these capacities. Human speech comprehension, poorly understood as a neurobiologic...

Serum levels of chemical elements in esophageal squamous cell carcinoma in Anyang, China: a case-control study based on machine learning methods.

BMJ open
OBJECTIVES: Esophageal squamous cell carcinoma (ESCC) is the predominant form of esophageal carcinoma with extremely aggressive nature and low survival rate. The risk factors for ESCC in the high-incidence areas of China remain unclear. We used machi...

Correcting Classifiers for Sample Selection Bias in Two-Phase Case-Control Studies.

Computational and mathematical methods in medicine
Epidemiological studies often utilize stratified data in which rare outcomes or exposures are artificially enriched. This design can increase precision in association tests but distorts predictions when applying classifiers on nonstratified data. Sev...