BACKGROUND: H3 influenza A viruses (IAV) have been shown to frequently cross the species barrier which can be an important factor in sustained transmission and spread. Machine learning methods have been widely explored for host prediction of IAV usin...
Lateral flow immunoassays (LFIAs) are widely used point-of-care (POC) diagnostic tools, but their limited sensitivity can hinder reliable diagnoses. To address this limitation, we developed a novel POC diagnostic platform for the highly sensitive det...
Outbreaks of SARS-CoV-2, first investigated as an unknown pathogen, have reflected the severe threat that pathogen X poses to public health and social security. Early and precise diagnosis and classification of infectious respiratory diseases with si...
Rapid point of care tests for respiratory infections are associated with high rates of false negative results which can drive empiric, and potentially inappropriate, antibiotic use. Because infectious pathogens alter VOC composition, unique VOC signa...
Influenza A viruses (IAVs) have historically posed significant public health threats, causing severe pandemics. Viral host specificity is typically constrained by host barriers, limiting the range of species that can be infected. However, these barri...
Antiviral peptides (AVPs) hold great potential for combating viral infections, yet their discovery and development remain challenging. In this study, we present a hybrid model combining Wasserstein Generative Adversarial Networks with Gradient Penalt...
Collection of systemic tissues from influenza A virus (IAV)-infected ferrets at a fixed timepoint post-inoculation represents a frequent component of risk assessment activities to assess the capacity of IAV to replicate systemically. However, few stu...
BACKGROUND: Influenza A virus (IAV) is a major global health threat, causing seasonal epidemics and occasional pandemics. Particularly, Influenza A viruses from avian species pose significant zoonotic threats, with PB2 adaptation serving as a critica...
RATIONALE AND OBJECTIVES: This study aimed to compare CT features of COVID-19 and Influenza A pneumonia, develop a diagnostic differential model, and explore a prognostic model for lesion resolution.
International journal of molecular sciences
Feb 6, 2025
Transient receptor potential vanilloid 4 (TRPV4) is a calcium-permeable cation channel critical for maintaining intracellular Ca homeostasis and is essential in regulating immune responses, metabolic processes, and signal transduction. Recent studies...
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