AIMC Topic: Intensive Care Units

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Association between fibrinogen levels and prognosis in critically bleeding patients: exploration of the optimal therapeutic threshold.

European journal of trauma and emergency surgery : official publication of the European Trauma Society
BACKGROUND: Severe bleeding is a leading cause of ICU admission and mortality. Fibrinogen plays a crucial role in prognosis, yet optimal thresholds and supplementation targets remain unclear.

Influence of the CONCERN Early Warning System on Unanticipated ICU Transfers, In-Hospital Mortality, and Length of Stay: Results from a Multi-site Pragmatic Randomized Controlled Clinical Trial.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Communicating Narrative Concerns Entered by RNs Early Warning System (CONCERN EWS) is a machine-learning predictive model that leverages nursing surveillance documentation patterns to predict deterioration risks for hospitalized patients. In a retros...

Predicting infections with multidrug-resistant organisms (MDROs) in neurocritical care patients with hospital-acquired pneumonia (HAP): development of a novel multivariate prediction model.

Microbiology spectrum
Hospital-acquired pneumonia (HAP) is prevalent in the neuro-intensive care unit (NICU), significantly increasing susceptibility to infections with multidrug-resistant organisms (MDROs), which result in high mortality rates and substantial healthcare ...

High procalcitonin level is related to blood stream infections, gram-negative pathogens, and ICU admission in infections of adult febrile cancer patients.

Journal of the Egyptian National Cancer Institute
BACKGROUND: Blood stream infection (BSI) represent a life-threatening condition. Thus, we aimed to investigate the role of procalcitonin (PCT) and C-reactive protein (CRP) tests in adult febrile patients with BSI and other clinical infections in hosp...

Explainable machine learning model for prediction of 28-day all-cause mortality in immunocompromised patients in the intensive care unit: a retrospective cohort study based on MIMIC-IV database.

European journal of medical research
OBJECTIVES: This study aimed to develop and validate an explainable machine learning (ML) model to predict 28-day all-cause mortality in immunocompromised patients admitted to the intensive care unit (ICU). Accurate and interpretable mortality predic...

Enriching patient populations in ICU trials: reducing heterogeneity through machine learning.

Current opinion in critical care
PURPOSE OF REVIEW: Despite the pivotal role of randomized controlled trials (RCTs) in critical care research, many have failed to demonstrate significant benefits, particularly in nutrition interventions. This review highlights how patient heterogene...

Clinical assessment of the criticality index - dynamic, a machine learning prediction model of future care needs in pediatric inpatients.

PloS one
OBJECTIVE: To assess patient characteristics and care factors that are associated with correct and incorrect predictions of future care locations (ICU vs. non-ICU) by the Criticality Index-Dynamic (CI-D), with the goal of enhancing the CI-D.

Explainable Machine Learning Model for Predicting Persistent Sepsis-Associated Acute Kidney Injury: Development and Validation Study.

Journal of medical Internet research
BACKGROUND: Persistent sepsis-associated acute kidney injury (SA-AKI) shows poor clinical outcomes and remains a therapeutic challenge for clinicians. Early identification and prediction of persistent SA-AKI are crucial.

Construction and validation of prognostic model for ICU mortality in cardiac arrest patients: an interpretable machine learning modeling approach.

European journal of medical research
BACKGROUND: The incidence and mortality of cardiac arrest (CA) is high. We developed interpretable machine learning models for early prediction of ICU mortality risk in patients diagnosed with CA.

Timing of kidney replacement therapy in critically ill patients: A call to shift the paradigm in the era of artificial intelligence.

Science progress
Acute kidney injury (AKI) is a common condition in intensive care units (ICUs) and is associated with high mortality rates, particularly when kidney replacement therapy (KRT) becomes necessary. The optimal timing for initiating KRT remains a subject ...