AIMC Topic: Kaplan-Meier Estimate

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Development and evaluation of a multivariable prediction model for overall survival in advanced stage pulmonary carcinoid using machine learning.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Evidence is limited on whether patients with advanced pulmonary carcinoid (APC) benefit from comprehensive pulmonary resection (CPR), chemotherapy, or radiotherapy. Existing prognostic models for APC are limited and do not guide treatment...

Pathology-based deep learning features for predicting basal and luminal subtypes in bladder cancer.

BMC cancer
BACKGROUND: Bladder cancer (BLCA) exists a profound molecular diversity, with basal and luminal subtypes having different prognostic and therapeutic outcomes. Traditional methods for molecular subtyping are often time-consuming and resource-intensive...

Impact of Sepsis Onset Timing on All-Cause Mortality in Acute Pancreatitis: A Multicenter Retrospective Cohort Study.

Journal of intensive care medicine
BackgroundSepsis complicates acute pancreatitis (AP), increasing mortality risk. Few studies have examined how sepsis and its onset timing affect mortality in AP. This study evaluates the association between sepsis occurrence and all-cause mortality ...

Developing practical machine learning survival models to identify high-risk patients for in-hospital mortality following traumatic brain injury.

Scientific reports
Machine learning (ML) offers precise predictions and could improve patient care, potentially replacing traditional scoring systems. A retrospective study at Emtiaz Hospital analyzed 3,180 traumatic brain injury (TBI) patients. Nineteen variables were...

Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study.

Arthritis research & therapy
OBJECTIVE: The aim of this study was to investigate the correlation between age, red cell distribution width (RDW) levels, and 180-day and 1-year mortality in giant cell arteritis (GCA) patients hospitalized or admitted to the ICU.

Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer.

Scientific reports
Gastric cancer (GC) is one of the most common tumors; one of the reasons for its poor prognosis is that GC cells can resist normal cell death process and therefore develop distant metastasis. Cuproptosis is a novel type of cell death and a limited nu...

Integrating multiomics analysis and machine learning to refine the molecular subtyping and prognostic analysis of stomach adenocarcinoma.

Scientific reports
Stomach adenocarcinoma (STAD) is a common malignancy with high heterogeneity and a lack of highly precise treatment options. We downloaded the multiomics data of STAD patients in The Cancer Genome Atlas (TCGA)-STAD cohort, which included mRNA, microR...

Personalized treatment strategies for breast adenoid cystic carcinoma: A machine learning approach.

Breast (Edinburgh, Scotland)
BACKGROUND: Breast adenoid cystic carcinoma (BACC) is a rare subtype of breast cancer that accounts for less than 0.1 % of all cases. This study was designed to assess the efficacy of various treatment approaches for BACC and to create the first web-...

Machine learning-based 28-day mortality prediction model for elderly neurocritically Ill patients.

Computer methods and programs in biomedicine
BACKGROUND: The growing population of elderly neurocritically ill patients highlights the need for effective prognosis prediction tools. This study aims to develop and validate machine learning (ML) models for predicting 28-day mortality in intensive...

Explainable Machine Learning to Predict Treatment Response in Advanced Non-Small Cell Lung Cancer.

JCO clinical cancer informatics
PURPOSE: Immune checkpoint inhibitors (ICIs) have demonstrated promise in the treatment of various cancers. Single-drug ICI therapy (immuno-oncology [IO] monotherapy) that targets PD-L1 is the standard of care in patients with advanced non-small cell...