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Kidney Neoplasms

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Machine Learning-Based Pathomics Model to Predict the Prognosis in Clear Cell Renal Cell Carcinoma.

Technology in cancer research & treatment
Clear cell renal cell carcinoma (ccRCC) is a highly lethal urinary malignancy with poor overall survival (OS) rates. Integrating computer vision and machine learning in pathomics analysis offers potential for enhancing classification, prognosis, and ...

Machine learning models predict the progression of long-term renal insufficiency in patients with renal cancer after radical nephrectomy.

BMC nephrology
BACKGROUND: Chronic Kidney Disease (CKD) is a common severe complication after radical nephrectomy in patients with renal cancer. The timely and accurate prediction of the long-term progression of renal function post-surgery is crucial for early inte...

Development of a centrosome amplification-associated signature in kidney renal clear cell carcinoma based on multiple machine learning models.

Computational biology and chemistry
BACKGROUND: Centrosome amplification (CA) has been shown to be capable of initiating tumorigenesis with metastatic potential and enhancing cell invasion. We were interested in discovering how centrosome amplification-associated signature affects the ...

Deep learning-based prediction of tumor aggressiveness in RCC using multiparametric MRI: a pilot study.

International urology and nephrology
OBJECTIVE: To investigate the value of multiparametric magnetic resonance imaging (MRI) as a non-invasive method to predict the aggressiveness of renal cell carcinoma (RCC) by developing a convolutional neural network (CNN) model and fusing it with c...

Radiomics for differential diagnosis of Bosniak II-IV renal masses via CT imaging.

BMC cancer
RATIONALE AND OBJECTIVES: The management of complex renal cysts is guided by the Bosniak classification system, which may be inadequate for risk stratification of patients to determine the appropriate intervention. Radiomics models based on CT imagin...

Integrated RNA sequencing analysis and machine learning identifies a metabolism-related prognostic signature in clear cell renal cell carcinoma.

Scientific reports
The connection between metabolic reprogramming and tumor progression has been demonstrated in an increasing number of researches. However, further research is required to identify how metabolic reprogramming affects interpatient heterogeneity and pro...

Leveraging explainable AI and large-scale datasets for comprehensive classification of renal histologic types.

Scientific reports
Recently, as the number of cancer patients has increased, much research is being conducted for efficient treatment, including the use of artificial intelligence in genitourinary pathology. Recent research has focused largely on the classification of ...

Interpretable CT Radiomics-based Machine Learning Model for Preoperative Prediction of Ki-67 Expression in Clear Cell Renal Cell Carcinoma.

Academic radiology
RATIONALE AND OBJECTIVES: To develop and externally validate interpretable CT radiomics-based machine learning (ML) models for preoperative Ki-67 expression prediction in clear cell renal cell carcinoma (ccRCC).