AIMC Topic: Lymphocytes
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Attention-guided multi-scale deep object detection framework for lymphocyte analysis in IHC histological images.
Microscopy (Oxford, England)
Feb 8, 2023
Tumor-infiltrating lymphocytes are specialized lymphocytes that can detect and kill cancerous cells. Their detection poses many challenges due to significant morphological variations, overlapping occurrence, artifact regions and high-class resemblanc...
Deep-learning-based MRI in the diagnosis of cerebral infarction and its correlation with the neutrophil to lymphocyte ratio.
Annals of palliative medicine
Nov 1, 2021
BACKGROUND: Dizziness is a common symptom in clinic, but there lacks an effective treatment method. This study sought to examine the efficiency of deep learning (DL)-based magnetic resonance imaging (MRI) in the diagnosis of cerebral infarction mainl...
Knowledge-based classification of fine-grained immune cell types in single-cell RNA-Seq data.
Briefings in bioinformatics
Sep 2, 2021
Single-cell RNA sequencing (scRNA-Seq) is an emerging strategy for characterizing immune cell populations. Compared to flow or mass cytometry, scRNA-Seq could potentially identify cell types and activation states that lack precise cell surface marker...
Evaluation of Combined Cancer Markers With Lactate Dehydrogenase and Application of Machine Learning Algorithms for Differentiating Benign Disease From Malignant Ovarian Cancer.
Cancer control : journal of the Moffitt Cancer Center
Jan 1, 2021
BACKGROUND: The differential diagnosis of ovarian cancer is important, and there has been ongoing research to identify biomarkers with higher performance. This study aimed to evaluate the diagnostic utility of combinations of cancer markers classifie...
THE PROJECT OF ANOTHER LOW-COST METAPHASE FINDER (SECOND REPORT-APPLICATION OF ARTIFICIAL INTELLIGENCE).
Radiation protection dosimetry
Dec 31, 2019
Biological dosimetry is used to estimate individual absorbed radiation dose by quantifying an appropriate biological marker. The most popular gold-standard marker is the appearance of dicentric chromosomes in metaphase. The metaphase finder is a tool...
Machine-Learning Approach for Modeling Myelosuppression Attributed to Nimustine Hydrochloride.
JCO clinical cancer informatics
Dec 1, 2018
PURPOSE: A major adverse effect arising from nimustine hydrochloride (ACNU) therapy for brain tumors is myelosuppression. Because its timing and severity vary among individual patients, the ACNU dose level has been adjusted in an empiric manner at in...
Image processing and machine learning in the morphological analysis of blood cells.
International journal of laboratory hematology
May 1, 2018
INTRODUCTION: This review focuses on how image processing and machine learning can be useful for the morphological characterization and automatic recognition of cell images captured from peripheral blood smears.
In vitro assessment of the cytotoxic, DNA damaging, and cytogenetic effects of hydroquinone in human peripheral blood lymphocytes.
Arhiv za higijenu rada i toksikologiju
Dec 20, 2017
This study investigated the mechanisms of hydroquinone toxicity and assessed the relationships between its cytotoxic, genotoxic, and cytogenetic effects tested at 8, 140, and 280 μg mL-1 in human peripheral blood lymphocytes exposed for 24 h. The out...
Genotoxicity in lead treated human lymphocytes evaluated by micronucleus and comet assays.
Indian journal of experimental biology
Aug 1, 2016
Lead (Pb) which plays a significant role in modern industry is related to a broad range of physiological, biochemical, behavioural and genetical dysfunctions. Its exposure leads to an increased frequency of genetic aberrations in humans. Hence, this ...
Elevated Preoperative Platelet to Lymphocyte Ratio Indicates Poor Survival in Patients with Resected High-grade Serous Ovarian Carcinoma.
Clinical laboratory
Aug 1, 2016
BACKGROUND: Platelet to lymphocyte ratio (PLR) is widely used as an inflammation-related cancer biomarker. However, since its prognostic importance in resected high-grade serous ovarian carcinoma (HGSC) is still unknown, we investigated the associati...
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