BMC medical informatics and decision making
Dec 5, 2019
BACKGROUND: Machine learning can assist with multiple tasks during systematic reviews to facilitate the rapid retrieval of relevant references during screening and to identify and extract information relevant to the study characteristics, which inclu...
BMC medical informatics and decision making
Dec 5, 2019
BACKGROUND: Accurately recognizing rare diseases based on symptom description is an important task in patient triage, early risk stratification, and target therapies. However, due to the very nature of rare diseases, the lack of historical data poses...
Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic stroke (AIS) clots. We analyzed 50 AIS blood clots retrieved using mechanical thrombectomy procedures. ...
To better control and manage harbor water quality is an important mission for coastal cities such as New York City (NYC). To achieve this, managers and governors need keep track of key quality indicators, such as temperature, pH, and dissolved oxygen...
With qPCR reaching thousands of reactions per run, assay validation needs automation. We applied support vector machine to qPCR analysis and we could identify reactions with 100% accuracy, dispensing them from further validation. We achieved a greatl...
Journal of chemical information and modeling
Dec 4, 2019
Developing Janus kinase 2 (JAK2) inhibitors has become a significant focus for small-molecule drug discovery programs in recent years because the inhibition of JAK2 may be an effective approach for the treatment of myeloproliferative neoplasm. Here, ...
It is difficult for visually impaired people to move indoors and outdoors. In 2018, world health organization (WHO) reported that there were about 253 million people around the world who were moderately visually impaired in distance vision. A navigat...
Chronic and recurrent opiate use injuries brain tissue and cause serious pathophysiological changes in hemodynamic and subsequent inflammatory responses. Prefrontal cortex (PFC) has been implicated in drug addiction. However, the mechanism underlying...
Journal of the Royal Society, Interface
Dec 4, 2019
There is still a significant gap between our understanding of neural circuits and the behaviours they compute-i.e. the computations performed by these neural networks (Carandini 2012 , 507-509. (doi:10.1038/nn.3043)). Cellular decision-making process...
Blood-borne small non-coding (sncRNAs) are among the prominent candidates for blood-based diagnostic tests. Often, high-throughput approaches are applied to discover biomarker signatures. These have to be validated in larger cohorts and evaluated by ...
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