The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
Feb 6, 2019
BACKGROUND: We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate rejection. In the present study we ex...
BACKGROUND: Traditional statistical approaches to prediction of outcomes have drawbacks when applied to large clinical databases. It is hypothesized that machine learning methodologies might overcome these limitations by considering higher-dimensiona...
Neural networks : the official journal of the International Neural Network Society
Feb 6, 2019
Humans and animals have the ability to continually acquire, fine-tune, and transfer knowledge and skills throughout their lifespan. This ability, referred to as lifelong learning, is mediated by a rich set of neurocognitive mechanisms that together c...
BACKGROUND: Wearable accelerometers have greatly improved measurement of physical activity, and the increasing popularity of smartwatches with inherent acceleration data collection suggest their potential use in the physical activity research domain;...
OBJECTIVE: Isocitrate dehydrogenase 1 (IDH1) mutation status is an independent favorable prognostic factor for glioblastoma (GBM) and is usually determined by sequencing or immunohistochemistry. An accurate prediction of IDH1 mutation status via noni...
About one in eight women in the U.S. will develop invasive breast cancer at some point in life. Breast cancer is the most common cancer found in women and if it is identified at an early stage by the use of mammograms, x-ray images of the breast, the...
Field-based sprint performance assessments rely on metrics derived from a simple model of sprinting dynamics parameterized by 2 constants, v and τ, which indicate a sprinter's maximal theoretical velocity and the time it takes to approach v, respecti...
In this paper, a reinforcement learning (RL)-based optimal adaptive control approach is proposed for the continuous infusion of a sedative drug to maintain a required level of sedation. To illustrate the proposed method, we use the common anesthetic ...
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