Proceedings of the National Academy of Sciences of the United States of America
Jun 24, 2025
Inspired by the challenges at the intersection of Evolutionary Game Theory and Machine Learning, we investigate a class of discrete-time multiagent reinforcement learning (MARL) dynamics in population/nonatomic congestion games, where agents have div...
Oral squamous cell carcinoma (OSCC) is an aggressive cancer with a poor prognosis. Oral epithelial dysplasia (OED) is a precancerous lesion associated with an increased risk of malignant transformation (MT) into OSCC. However, current histopathologic...
BACKGROUND: Chronic kidney disease (CKD) is a major global public health issue, with a steadily increasing incidence. Urinary protein detection serves as a crucial indicator for the diagnosis, monitoring and management of CKD. However, current method...
Machine learning (ML) tools offer new opportunities in drug discovery, especially for enhancing our understanding of molecular interactions with biological systems. This study develops a comprehensive quantitative structure-retention relationship (QS...
Progress in neuro-psychopharmacology & biological psychiatry
Jun 20, 2025
The zebrafish (Danio rerio) has emerged as a powerful organism in behavioral neuroscience, offering invaluable insights into the neural circuits and molecular pathways underlying complex behaviors. Although the knowledge of zebrafish behavioral reper...
Progress in neuro-psychopharmacology & biological psychiatry
Jun 20, 2025
BACKGROUND: For suicide in major depression disorder, it is urgent to seek for a reliable neuroimaging biomarker with interpretable links to molecular tissue signatures. Accordingly, we developed an ensemble learning scheme over transcriptome-defined...
Conotoxins are a family of highly toxic neurotoxins composed of cysteine-rich peptides produced by marine cone snails. The most lethal cone snail species to humans is with fatality rates of up to ∼65% from a single sting, which is caused mostly by t...
Androgenetic alopecia (AGA), the most common form of hair loss, has been linked to dysbiosis of the scalp microbiome. In this study, we collected microbiome samples from the frontal baldness and occipital regions of patients with varying stages of AG...
The Journal of clinical endocrinology and metabolism
Jun 17, 2025
BACKGROUND: In recent years, there has been increasing data showing that the risk of acute pancreatitis (AP) is increased in patients using methimazole (MMI). The aim of this population-based study was to investigate the association between drugs use...
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