AIMC Topic: Machine Learning

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Machine learning in colorectal polyp surveillance: A paradigm shift in post-endoscopic mucosal resection follow-up.

World journal of gastroenterology
Colorectal cancer remains a major health concern, with colorectal polyps as key precursors. Endoscopic mucosal resection (EMR) is a common treatment, but recurrence rates remain high. Traditional surveillance strategies rely on polyp characteristics ...

Update on the detection of frailty in older adults: a multicenter cohort machine learning-based study protocol.

Aging
BACKGROUND: This study aims to investigate the relationship between muscle activation variables assessed via ultrasound and the comprehensive assessment of geriatric patients, as well as to analyze ultrasound images to determine their correlation wit...

Machine learning identification of enhancers in the rhesus macaque genome.

Neuron
Nonhuman primate (NHP) neuroanatomy and cognitive complexity make NHPs ideal models to study human neurobiology and disease. However, NHP circuit-function investigations are limited by the availability of molecular reagents that are effective in NHPs...

Diagnostic performance of actigraphy in Alzheimer's disease using a machine learning classifier - a cross-sectional memory clinic study.

Alzheimer's research & therapy
BACKGROUND: Movement patterns, activity levels and circadian rhythm are altered in Alzheimer's disease (AD) and can be assessed by actigraphy using wearable sensors. We aimed to determine the diagnostic performance of actigraphy in AD in a memory cli...

Early prediction of bone destruction in rheumatoid arthritis through machine learning analysis of plasma metabolites.

Arthritis research & therapy
BACKGROUND: To develop a predictive model for bone destruction in patients with rheumatoid arthritis (RA), based on the characteristics of plasma metabolites and common clinical indicators.

GNNs and ensemble models enhance the prediction of new sRNA-mRNA interactions in unseen conditions.

BMC bioinformatics
Bacterial small RNAs (sRNAs) are pivotal in post-transcriptional regulation, affecting functions like virulence, metabolism, and gene expression by binding specific mRNA targets. Identifying these targets is crucial to understanding sRNA regulation a...

Accurate prediction of virulence factors using pre-train protein language model and ensemble learning.

BMC genomics
BACKGROUND: As bacterial pathogens develop increasing resistance to antibiotics, strategies targeting virulence factors (VFs) have emerged as a promising and effective approach for treating bacterial infections. Existing methods mainly relied on sequ...

A self-supervised learning approach for high throughput and high content cell segmentation.

Communications biology
In principle, ML/AI-based algorithms should enable rapid and accurate cell segmentation in high-throughput settings. However, reliance on large training datasets, human input, computational expertise, and limited generalizability has prevented this g...

A machine learning based prediction model for short term efficacy of nasopharyngeal carcinoma.

Scientific reports
The radiological dosimetric parameters and clinical features were screened by machine learning to construct a prediction model for the short-term efficacy of locally advanced Nasopharyngeal Carcinoma (LANPC). Patients diagnosed with Nasopharyngeal Ca...

Predictive machine learning and multimodal data to develop highly sensitive, composite biomarkers of disease progression in Friedreich ataxia.

Scientific reports
Friedreich ataxia (FRDA) is a rare, inherited progressive movement disorder for which there is currently no cure. The field urgently requires more sensitive, objective, and clinically relevant biomarkers to enhance the evaluation of treatment efficac...