AIMC Topic: Machine Learning

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Screening of glioma susceptibility SNPs and construction of risk models based on machine learning algorithms.

BMC neurology
BACKGROUND: Glioma is a common primary malignant brain tumor. This study aimed to develop a predictive model for glioma risk by these screened key SNPs in the Chinese Han population.

Research on ischemic stroke risk assessment based on CTA radiomics and machine learning.

BMC medical imaging
BACKGROUND: The study explores the value of a model constructed by integrating CTA-based carotid plaque radiomic features, clinical risk factors, and plaque imaging characteristics for prognosticating the risk of ischemic stroke.

Interpretable machine learning models for predicting childhood myopia from school-based screening data.

Scientific reports
This study assessed the efficacy of various diagnostic indicators and machine learning (ML) models in predicting childhood myopia. A total of 2,365 children aged 5-12 years were included in the study. The participants were exposed to non-cycloplegic ...

Machine learning and multi-omics analysis reveal key regulators of proneural-mesenchymal transition in glioblastoma.

Scientific reports
Glioblastoma (GBM) is classified into subtypes according to the molecular expression profile; the proneural subtype has a relatively good prognosis, and the mesenchymal type is the most aggressive form with the worst prognosis. GBM undergoes proneura...

Predicting carbapenem-resistant Pseudomonas aeruginosa infection risk using XGBoost model and explainability.

Scientific reports
The prevalence and spread of carbapenem-resistant Pseudomonas aeruginosa (CRPA) is a global public health problem. This study aims to identify the risk factors of CRPA infection and construct a machine learning model to provide a prediction tool for ...

Machine learning-based integration develops relapse related signature for predicting prognosis and indicating immune microenvironment infiltration in breast cancer.

Scientific reports
Breast cancer is the most common type of cancer in women, and while current treatments can cure the majority of early-stage primary BC cases, recurrence remains a significant challenge. Traditional methods of assessing patient prognosis, such as AJCC...

Harnessing vaginal inflammation and microbiome: a machine learning model for predicting IVF success.

NPJ biofilms and microbiomes
Humans are the only species with a commensal Lactobacillus-dominant vaginal microbiota. Reproductive tract microbes have been linked to fertility outcomes, as has intrauterine inflammation, suggesting immune response may mediate adverse outcomes. In ...

Ensemble of weak spectral total-variation learners: a PET-CT case study.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Solving computer vision problems through machine learning, one often encounters lack of sufficient training data. To mitigate this, we propose the use of ensembles of weak learners based on spectral total-variation (STV) features (Gilboa G. 2014 A to...

Designing diverse and high-performance proteins with a large language model in the loop.

PLoS computational biology
We present a protein engineering approach to directed evolution with machine learning that integrates a new semi-supervised neural network fitness prediction model, Seq2Fitness, and an innovative optimization algorithm, biphasic annealing for diverse...

Machine learning-based prediction model for cognitive impairment risk in patients with chronic kidney disease.

PloS one
BACKGROUND: The high prevalence of cognitive impairment (CI) in Chronic kidney disease (CKD) patients impacts their quality of life and prognosis, yet risk prediction models for CI in this population remain underexplored.