The global resurgence of dengue presents an ongoing challenge for public health systems, particularly in low- and middle-income countries (LMICs) where conventional early warning systems (EWS) often suffer from reporting delays and under-detection. W...
Journal of chemical theory and computation
Aug 5, 2025
Binding free energies are key elements in understanding and predicting the strength of protein-drug interactions. While classical free energy simulations yield good results for many purely organic ligands, drugs, including transition metal atoms, oft...
Journal of chemical information and modeling
Aug 5, 2025
Machine learning has been increasingly utilized in the field of biomedical research to accelerate the drug discovery process. In recent years, the emergence of quantum computing has led to the extensive exploration of quantum machine learning algorit...
Current evidence for predictive models of post-stroke depression (PSD) risk based on machine learning (ML) remains limited. The aim of this study is to develop a superior predictive model based on ML algorithms for PSD in the Chinese population. We r...
Today, the problem of using social media to spread false information is not only widespread but also quite serious. The extensive dissemination of fake news, regardless of whether it is produced by human beings or computer programs, has a negative im...
Antiretroviral therapy (ART) has transformed HIV from a rapidly progressive and fatal disease to a chronic disease with limited impact on life expectancy. However, people living with HIV(PLWHs) faced high critical illness risk due to the increased pr...
BMC medical informatics and decision making
Aug 5, 2025
BACKGROUND: Attention deficit/hyperactivity disorder (ADHD) is the most common neurodevelopmental disorder. Gender disparities in the diagnosis of ADHD have been reported, suggesting that females tend to be diagnosed later in life than males are. The...
BACKGROUND: In emergency departments, residents and physicians interpret X-rays to identify fractures, with distal radius fractures being the most common in children. Skilled radiologists typically ensure accurate readings in well-resourced hospitals...
BACKGROUND: Delirium frequently occurs as a severe complication among patients with acute pancreatitis (AP), contributing to extended hospital stays, higher mortality rates, and lasting cognitive deficits. The pathogenesis of delirium in this setting...
The circadian clock of plants contributes to their survival and fitness. However, understanding clock function at the transcriptome level and its response to the environment requires assaying across high resolution time-course experiments. Generating...
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