AIMC Topic: Machine Learning
Clear Filters Showing 291 to 300 of 31198 articles
Data-driven protease engineering by DNA-recording and epistasis-aware machine learning.
Nature communications
Jul 1, 2025
Protein engineering has recently seen tremendous transformation due to machine learning (ML) tools that predict structure from sequence at unprecedented precision. Predicting catalytic activity, however, remains challenging, restricting our capabilit...
Charting γ-secretase substrates by explainable AI.
Nature communications
Jul 1, 2025
Proteases recognize substrates by decoding sequence information-an essential cellular process elusive when recognition motifs are absent. Here, we unravel this problem for γ-secretase, an intramembrane-cleaving protease associated with Alzheimer's di...
Enhanced role of the entorhinal cortex in adapting to increased working memory load.
Nature communications
Jul 1, 2025
In daily life, we frequently encounter varying demands on working memory (WM), yet how the brain adapts to high WM load remains unclear. To address this question, we recorded intracranial EEG from hippocampus, entorhinal cortex (EC), and lateral temp...
Evaluation of normalization strategies for mass spectrometry-based multi-omics datasets.
Metabolomics : Official journal of the Metabolomic Society
Jul 1, 2025
INTRODUCTION: Data normalization is crucial for multi-omics integration, reducing systematic errors and maximizing the likelihood of discovering true biological variation. Most studies assess normalization for a single omics type or use datasets from...
Prediction of axillary lymph node metastasis in triple negative breast cancer using MRI radiomics and clinical features.
Scientific reports
Jul 1, 2025
To develop and validate a machine learning-based prediction model to predict axillary lymph node (ALN) metastasis in triple negative breast cancer (TNBC) patients using magnetic resonance imaging (MRI) and clinical characteristics. This retrospective...
Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.
Scientific reports
Jul 1, 2025
Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. This study aimed to investigate the role of CMRGs in OA and provide new insights into its treatment. ...
A highly generalized federated learning algorithm for brain tumor segmentation.
Scientific reports
Jul 1, 2025
Brain image segmentation plays a pivotal role in modern healthcare by enabling precise diagnosis and treatment planning. Federated Learning (FL) enables collaborative model training across institutions while safeguarding sensitive patient data. The i...
Unveiling the mechanisms and promising molecular targets of curcumin in pancreatic cancer through multi-dimensional data.
Scientific reports
Jul 1, 2025
Pancreatic cancer (PC) is a highly aggressive and fatal malignancy, primarily affecting older males. Curcumin, a potential anti-cancer agent, has been shown to regulate key molecules in cancer progression, but its specific mechanisms in PC remain unc...
Development and validation of a modified SOFA score for mortality prediction in candidemia patients.
Scientific reports
Jul 1, 2025
Candidemia is a life-threatening bloodstream infection associated with high mortality rates, particularly in critically ill patients. Accurate risk stratification is crucial for timely intervention and could improve patient outcomes. This study aimed...
Predictive model of ulcerative colitis syndrome with ensemble learning and interpretability methods.
Scientific reports
Jul 1, 2025
In recent years, the prevalence of chronic diseases such as Ulcerative Colitis (UC) has increased, bringing a heavy burden to healthcare systems. Traditional Chinese Medicine (TCM) stands out for its cost-effective and efficient treatment modalities,...
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31155
- Neural Networks, Computer 29777
- Algorithms 26923
- Deep Learning 26427
- Artificial Intelligence 24367
- Robotics 13323
- Image Processing, Computer-Assisted 9556
- Retrospective Studies 9139
- Magnetic Resonance Imaging 6201
- Reproducibility of Results 5603
- Tomography, X-Ray Computed 4779
- Support Vector Machine 4697
- Computational Biology 4248
- Brain 4056
- Computer Simulation 3887
Recent Journals
- Scientific reports 6099
- Sensors (Basel, Switzerland) 4794
- PloS one 4051
- Neural networks : the official journal of the International Neural Network Society 2930
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1868
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1137
- Journal of chemical information and modeling 1006
- Nature communications 962
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 862
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 830