AIMC Topic: Machine Learning

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Conditional similarity triplets enable covariate-informed representations of single-cell data.

BMC bioinformatics
BACKGROUND: Single-cell technologies enable comprehensive profiling of diverse immune cell-types through the measurement of multiple genes or proteins per individual cell. In order to translate immune signatures assayed from blood or tissue into powe...

Ultrasonic-Based Radiomics Signature With Machine Learning for Differentiating Prognostic Subsets of Pediatric Peripheral Neuroblastic Tumors: A Retrospective Study.

Ultrasound in medicine & biology
OBJECTIVE: To construct and select a better model based on ultrasonic-based radiomics features and clinical characteristics for prognostic subsets of pediatric neuroblastic tumors.

Classification and regression machine learning models for predicting mixed toxicity of carbamazepine and its transformation products.

Environmental research
Carbamazepine (CBZ) and its transformation products (TPs) often occur in aquatic environments in the form of mixtures, posing potential risks to ecosystems. However, establishing standardized protocols for synthesizing, isolating, and acquiring these...

Learning robust medical image segmentation from multi-source annotations.

Medical image analysis
Collecting annotations from multiple independent sources could mitigate the impact of potential noises and biases from a single source, which is a common practice in medical image segmentation. However, learning segmentation networks from multi-sourc...

Integration of single-cell and bulk RNA sequencing data using machine learning identifies oxidative stress-related genes LUM and PCOLCE2 as potential biomarkers for heart failure.

International journal of biological macromolecules
Oxidative stress (OS) is a pivotal mechanism driving the progression of cardiovascular diseases, particularly heart failure (HF). However, the comprehensive characterisation of OS-related genes in HF remains largely unexplored. In the present study, ...

Unveiling NLR pathway signatures: EP300 and CPN60 markers integrated with clinical data and machine learning for precision NASH diagnosis.

Cytokine
BACKGROUND: Given the increasing prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) and non-alcoholic steatohepatitis (NASH), there is a critical need for accurate non-invasive early diagnostic markers.

Discovering Vitamin-D-Deficiency-Associated Factors in Korean Adults Using KNHANES Data Based on an Integrated Analysis of Machine Learning and Statistical Techniques.

Nutrients
: Vitamin D deficiency (VDD) is a global health concern associated with metabolic disease and immune dysfunction. Despite known risk factors like limited sun exposure, diet, and lifestyle, few studies have explored these factors comprehensively on a ...

Associations between age, red cell distribution width and 180-day and 1-year mortality in giant cell arteritis patients: mediation analyses and machine learning in a cohort study.

Arthritis research & therapy
OBJECTIVE: The aim of this study was to investigate the correlation between age, red cell distribution width (RDW) levels, and 180-day and 1-year mortality in giant cell arteritis (GCA) patients hospitalized or admitted to the ICU.

Comparison of time-to-event machine learning models in predicting biliary complication and mortality rate in liver transplant patients.

Scientific reports
Post-Liver transplantation (LT) survival rates stagnate, with biliary complications (BC) as a major cause of death. We analyzed longitudinal data with a median 19-month follow-up. BC was diagnosed with ultrasounds and MRCP. Missing data was imputed u...

Correlation of rivaroxaban solubility in mixed solvents for optimization of solubility using machine learning analysis and validation.

Scientific reports
In this study, the solubility of rivaroxaban, a poorly water-soluble drug, was investigated in mixed solvent systems to address challenges in pharmaceutical formulation and bioavailability enhancement. Solubility optimization is essential for the eff...