AIMC Topic: Machine Learning

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Comprehensive interaction modeling with machine learning improves prediction of disease risk in the UK Biobank.

Nature communications
Understanding how risk factors interact to jointly influence disease risk can provide insights into disease development and improve risk prediction. Here we introduce survivalFM, a machine learning extension to the widely used Cox proportional hazard...

Comparing the Performance of Machine Learning Models and Conventional Risk Scores for Predicting Major Adverse Cardiovascular Cerebrovascular Events After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: Machine learning (ML) models may offer greater clinical utility than conventional risk scores, such as the Thrombolysis in Myocardial Infarction (TIMI) and Global Registry of Acute Coronary Events (GRACE) risk scores. However, there is a ...

Performance of Machine Learning in Diagnosing KRAS (Kirsten Rat Sarcoma) Mutations in Colorectal Cancer: Systematic Review and Meta-Analysis.

Journal of medical Internet research
BACKGROUND: With the widespread application of machine learning (ML) in the diagnosis and treatment of colorectal cancer (CRC), some studies have investigated the use of ML techniques for the diagnosis of KRAS (Kirsten rat sarcoma) mutation. Neverthe...

Predicting Pathological Complete Response Following Neoadjuvant Therapy in Patients With Breast Cancer: Development of Machine Learning-Based Prediction Models in a Retrospective Study.

JMIR cancer
BACKGROUND: Breast cancer is the most prevalent form of cancer worldwide, with 2.3 million new diagnoses in 2022. Recent advancements in treatment have led to a shift in the use of chemotherapy-targeted immunotherapy from a postoperative adjuvant to ...

Assessment and prediction models for the quantitative and qualitative reserve of the ovary using machine learning.

Journal of ovarian research
BACKGROUND: The age-related decline of fertility is caused by a reduction of the ovarian reserve, which is represented by the number and quality of oocytes in the ovaries. Anti-Müllerian hormone (AMH) is considered one of the most useful markers of t...

Establishment of an interpretable MRI radiomics-based machine learning model capable of predicting axillary lymph node metastasis in invasive breast cancer.

Scientific reports
This study sought to develop a radiomics model capable of predicting axillary lymph node metastasis (ALNM) in patients with invasive breast cancer (IBC) based on dual-sequence magnetic resonance imaging(MRI) of diffusion-weighted imaging (DWI) and dy...

Comparison of conventional and radiomics-based analysis of myocardial infarction using multimodal non-linear optical microscopy.

Scientific reports
Myocardial infarction, a leading cause of mortality worldwide, leaves survivors at significant risk of recurrence caused by scar-related re-entrant ventricular tachyarrhythmias. Effective treatment with ablation therapy requires a precise guidance sy...

Integrating bulk and single cell sequencing data to identify prognostic biomarkers and drug candidates in HBV associated hepatocellular carcinoma.

Scientific reports
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined. In this study, 53 immune-related key genes invol...

Type of pre-existing chronic conditions and their associations with Merkel cell carcinoma (MCC) treatment: Prediction and interpretation using machine learning methods.

PloS one
OBJECTIVE: This study examined the prevalence of pre-existing chronic conditions and their association with the receipt of specific cancer-directed treatments among older adults with incident primary Merkel Cell Carcinoma (MCC) using novel predictive...

An innovative efficiency of incubator to enhance organization supportive business using machine learning approach.

PloS one
Many small businesses and startups struggle to adjust their operational plans to quickly changing market and financial situations. Traditional data-driven techniques often miss possibilities and waste resources. Our unique approach, Unified Statistic...