Computer methods and programs in biomedicine
Oct 23, 2024
BACKGROUND AND OBJECTIVE: Low-dose computed tomography (LDCT) screening has shown promise in reducing lung cancer mortality; however, it suffers from high false positive rates and a scarcity of available annotated datasets. To overcome these challeng...
Noise detection in ambulatory electrocardiography is investigated as a machine learning binary classification problem on a set of twelve noise indices. Ten of these noise indices are replicated from relevant scientific literature. Two novel noise ind...
Attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental condition marked by inattention and impulsivity, linked to disruptions in functional brain connectivity and structural alterations in large-scale brain networks. Although sensory...
Peptide hormones were first used in medicine in the early 20th century, with the pivotal event being the isolation and purification of insulin in 1921. These hormones are integral to a sophisticated system that emerged early in evolution to regulate ...
DNA-encoded library (DEL) technology is an effective method for small molecule drug discovery, enabling high-throughput screening against target proteins. While DEL screening produces extensive data, it can reveal complex patterns not easily recogniz...
Journal of chemical information and modeling
Oct 23, 2024
In the rapidly evolving field of drug discovery, high-throughput screening (HTS) is essential for identifying bioactive compounds. This study introduces a novel application of data valuation, a concept for evaluating the importance of data points bas...
The field of neuropathology, a subspecialty of pathology which studies the diseases affecting the nervous system, is experiencing significant changes due to advancements in artificial intelligence (AI). Traditionally reliant on histological methods a...
Ecotoxicology and environmental safety
Oct 23, 2024
Micro/nanoplastics (MNPs) and heavy metals (HMs) coexist worldwide. Existing studies have reported different or even contradictory toxic effects of co-exposure to MNPs and HMs on plants, which may be related to various influencing factors. In this st...
Ecotoxicology and environmental safety
Oct 23, 2024
BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of mortality globally. Environmental pollutants, specifically volatile organic compounds (VOCs), have been identified as significant risk factors. This study aims to develop a machine l...
The Kaohsiung journal of medical sciences
Oct 23, 2024
Universal neonatal hepatitis B virus (HBV) vaccination and the advent of direct-acting antivirals (DAA) against hepatitis C virus (HCV) have reshaped the epidemiology of chronic liver diseases. However, some aspects of the management of chronic liver...
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