BACKGROUND: KMT2B-related dystonia is a childhood-onset movement disorder. This study investigated a novel KMT2B gene variant using whole exome sequencing (WES) and bioinformatics analysis, and expanded the known clinical spectrum of KMT2B-related dy...
Biomedical physics & engineering express
Nov 6, 2025
Positron Emission Tomography/Magnetic Resonance () offers benefits over PET/CT including simultaneous PET and MR acquisition, intrinsic spatial registration accuracy, MR-based functional information, and superior soft tissue contrast. However, accura...
Sex differences in mental health become more evident across adolescence, with a two-fold increase of prevalence of mood disorders in females compared to males. The brain underpinnings remain understudied. Here, we investigated the role of age, pubert...
Accurate detection and classification of clinically significant prostate cancer remain critical challenges in medical imaging. Despite numerous studies focusing on feature extraction and classification, none have systematically assessed the impact of...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nov 5, 2025
Computer programming is a cornerstone of modern society, yet little is known about how the human brain enables this recently invented cultural skill. According to the neural recycling hypothesis, cultural skills (e.g., reading, math) repurpose preexi...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Nov 5, 2025
In humans, the superior temporal sulcus (STS) combines auditory and visual information. However, the extent to which it relies on visual information from the ventral or dorsal stream remains uncertain. To address this, we analyzed open-source functio...
BACKGROUND: We aim to assess the diagnosis performance of an ensemble machine learning (ML) based radiomic analysis of multiparametric cardiac magnetic resonance (CMR) to differentiate light chain cardiac amyloidosis (AL-CA) and hypertrophic cardiomy...
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by a wide spectrum of motor and non-motor symptoms, often leading to delayed or inaccurate diagnosis. Conventional diagnostic methods frequently suffer from limited se...
The corpus callosum (CC) is the largest set of white matter fibers connecting the two hemispheres of the brain. In humans, it is essential for coordinating sensorimotor responses and performing associative or executive functions. Identifying which ge...
This study aimed to develop and validate an interpretable radiomics-based machine learning model using contrast-enhanced T1-weighted imaging (CE-T1WI) to differentiate glioblastoma (GB) from primary central nervous system lymphoma (PCNSL), while comp...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.