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A Proof-of-Concept Development on Speech Analysis for Concussion Detection.

Studies in health technology and informatics
Speech signal analysis to support objective clinical decision-making has gained immense interest, especially in neurological disorders. This research assessed the feasibility of speech analysis on the detection of concussions. Using a speech dataset ...

Development and Validation of Machine-Learning Algorithms to Predict the Onset of Depression Using Electronic Health Record Data: A Prognostic Modeling Study.

Studies in health technology and informatics
INTRODUCTION: Early detection and intervention are crucial for reducing the impacts of depression and associated healthcare costs. Few studies have used electronic health records (EHR) and machine learning (ML) with a longitudinal design to predict d...

Development of Multivariable Prediction Models for 30-Day Risk of Readmission After COPD Hospital Admission: A Retrospective Cohort Study Using Electronic Medical Record Data from 7 Hospitals.

Studies in health technology and informatics
BACKGROUND: Approximately 20% of patients who are discharged from hospital for an acute exacerbation of COPD (AECOPD) are readmitted within 30 days. Prediction scores are helpful to identify those who are at higher risk of readmission, such that they...

Lower Extremity Bypass Surveillance and Peak Systolic Velocities Value Prediction Using Recurrent Neural Networks.

Studies in health technology and informatics
Routine duplex ultrasound surveillance is recommended after femoral-popliteal and femoral-tibial-pedal vein bypass grafts at various post-operative intervals. Currently, there is no systematic method for bypass graft surveillance using a set of peak ...

Predicting Diabetes Using Convolutional Neural Networks and EKG Entropy Analysis.

Studies in health technology and informatics
Heart Rate Variability (HRV) is associated with diabetic complications. This analysis can quantify changes in heart rate variability, and it may help detect early alterations in diabetes. This study aimed to design and validate a Convolutional Neural...

Constrained Tensor Factorization for Cancer Phenotyping and Mortality Prediction.

Studies in health technology and informatics
Electronic health records (EHR) enable machine learning methods like tensor factorization to extract computational phenotypes. Using Northwestern Medicine data (2000-2015), we analyzed breast, prostate, colorectal, and lung cancer cohorts to predict ...

Predicting Nephrectomy Risk in Patients with Renal Cancer Using Real-World Electronic Health Records.

Studies in health technology and informatics
Nephrectomy, the surgical removal of a kidney, is a critical treatment for renal cancer, and predicting its likelihood can help guide clinical decision-making and optimize preoperative planning. This study utilized real-world electronic health record...

Detection of Brain Cancer Using Genome-wide Cell-free DNA Fragmentomes.

Cancer discovery
UNLABELLED: Diagnostic delays in patients with brain cancer are common and can impact patient outcome. Development of a blood-based assay for detection of brain cancers could accelerate brain cancer diagnosis. In this study, we analyzed genome-wide c...

Machine learning diagnosis of cognitive impairment and dementia in harmonized older adult cohorts.

Alzheimer's & dementia : the journal of the Alzheimer's Association
INTRODUCTION: Clinical diagnosis (normal cognition, mild cognitive impairment [MCI], dementia) is critical for understanding cognitive impairment and dementia but can be resource intensive and subject to inconsistencies due to complex clinical judgme...

Predicting p53 Status in IDH-Mutant Gliomas Using MRI-Based Radiomic Model.

Cancer medicine
OBJECTIVES: Accurate and noninvasive detection of p53 status in isocitrate dehydrogenase mutant (IDH-mt) glioma is clinically meaningful for molecular stratification of glioma, yet it remains challenging. We aimed to investigate the diagnostic effica...