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Piezo-Nanowired Stem Cells: Ultrasound-Powered Neuronal Commitment for Rapid Neural Circuit Reconstruction after Traumatic Brain Injury.

ACS nano
The inherently constrained regenerative capacity of neuronal tissue poses a major obstacle to repairing traumatic brain injury. While neural stem cell transplantation holds promise, its efficacy is constrained by slow and inefficient neuronal differe...

Cardiovascular risk assessment enhanced by automated machine learning in a multi-phase study.

Scientific reports
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, and current predictors such as lipoprotein (a) [Lp(a)] and risk scores have limitations. Automated machine learning (AutoML) offers the potential to improve CVD risk prediction ...

A machine learning tool for predicting newly diagnosed osteoporosis in primary healthcare in the Stockholm Region.

Scientific reports
Improving accuracy and timeliness for osteoporosis diagnosis could help prevent fragility fractures, morbidity, and mortality for older individuals. Osteoporosis is an often silent health condition, especially as regards vertebral fractures, and WHO ...

Rapid Liver Fibrosis Evaluation Using the UNet-ResNet50-32 × 4d Model in Magnetic Resonance Elastography: Retrospective Study.

JMIR medical informatics
BACKGROUND: Liver fibrosis is a pathological outcome of chronic liver injury and a hallmark of multiple chronic liver diseases. Magnetic resonance elastography (MRE) provides a non-invasive modality for evaluating the severity of liver fibrosis.

Efficacy of Telemedical Interventional Management in Patients with Coronary Heart Disease Undergoing Percutaneous Coronary Intervention: Randomized Controlled Trial.

Journal of medical Internet research
BACKGROUND: Coronary heart disease (CHD) continues to be a leading cause of global morbidity and mortality, with patients undergoing percutaneous coronary intervention (PCI) facing a significant risk of recurrent cardiovascular events. While secondar...

Age-specific prevalence and predictors of lifetime suicide attempts using machine learning in Chinese adults: a nationwide multi-centre survey.

Epidemiology and psychiatric sciences
AIMS: The epidemiology and age-specific patterns of lifetime suicide attempts (LSA) in China remain unclear. We aimed to examine age-specific prevalence and predictors of LSA among Chinese adults using machine learning (ML).

Automated Multimodal Image Registration for Prostate Cancer Using Squeeze-and-Excitation ResNet with Thin Plate Spline Transformation: A Deep Learning Approach.

Medical science monitor : international medical journal of experimental and clinical research
BACKGROUND Accurate spatial correlation between preoperative prostate MRI and post-prostatectomy histopathology is critical for improving prostate cancer diagnosis, treatment planning, and MRI interpretation. Current manual registration methods are t...

Exploring the role of cytochrome P450 family 1 subfamily B member 1 and quercetin in modulating neuropathic pain after spinal cord injury.

Molecular medicine reports
Spinal cord injury (SCI) represents a notable global health challenge, with neuropathic pain (NP) being a common complication that intensifies patient suffering. Existing research tends to overlook the temporal aspects of NP and fails to offer target...

Applying spectral analysis to the arterial pulse to discriminate cardiovascular side effects following administration of Moderna's mRNA-1273 vaccine.

European journal of pharmacology
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated strong efficacy in preventing symptomatic disease, but adverse cardiovascular side effects have been reported. This study investigated whether noninvasive...

Hierarchical dynamic coding coordinates speech comprehension in the human brain.

Proceedings of the National Academy of Sciences of the United States of America
Speech comprehension involves transforming an acoustic waveform into meaning. To do so, the human brain generates a hierarchy of features that converts the sensory input into increasingly abstract language properties. However, little is known about h...