AIMC Topic: Metal Nanoparticles

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Ag+ modified paper-based SERS combined with SiPLS for quantitative detection of soluble As3+ in aqueous realgar solutions.

Analytica chimica acta
The detection of soluble arsenic in realgar and its preparations is crucial for toxicity evaluation. Therefore, surface-enhanced Raman spectroscopy (SERS) combined with machine learning was applied for the rapid detection of soluble As3+ in realgar a...

Advancing Medical Diagnostics: Rapid, Label-Free Detection and Differentiation of Shiga Toxin Variants in Human Serum Using a Cost-Effective PCA-Assisted SERS Platform.

ACS applied materials & interfaces
Shiga toxins-producing (STEC) are zoonotic pathogens causing severe diseases such as hemorrhagic colitis (HC) and hemolytic uremic syndrome (HUS). Infections caused by STEC represent a public health concern due to the severity of the possible outcom...

Artificial Intelligence-Coupled Self-Calibrating SERS Spectroscopy for Robust Clinical Diagnosis of Diabetes and Associated Complications.

Analytical chemistry
Diabetes mellitus (DM), a prevalent metabolic disorder, poses significant diagnostic and therapeutic challenges, especially, in the early stage diagnosis of diabetes related complications. Accurate early stage diagnosis of diabetes and its complicati...

Multifunctional Ag-PDA@PCM composite eutectogel based electronic skin for personal thermal management and a machine learning assisted wearable sensor.

Journal of materials chemistry. B
Inspired by the perception and temperature regulation functionalities of human skin, multifunctional electronic skin (E-skin) for human motion detection and personal thermal management has attracted great attention. Here, we design an E-skin with str...

Silver-Programmed Dual-Optical Au Nanostructures and Machine Learning for Intelligent Biosensing.

Analytical chemistry
The evolution of biosensors demands synergistic improvements in signal transduction and data processing. We present a universal biosensing platform that combines dual-mode signal responses from silver-modulated gold nanorods (AuNRs) and gold-silver n...

A Single-step Platinum Nanoparticle-Enhanced Lateral Flow Immunoassay Platform for Rapid Detection of Influenza A Virus.

ACS infectious diseases
Lateral flow immunoassays (LFIAs) are widely used point-of-care (POC) diagnostic tools, but their limited sensitivity can hinder reliable diagnoses. To address this limitation, we developed a novel POC diagnostic platform for the highly sensitive det...

Gemini SERS for Cross-Category Biomarker Detection and Early Warning of Sudden Cardiac Death in Acute Coronary Syndrome.

ACS nano
Simultaneous detection of metabolites and proteins─two chemically and functionally distinct classes of biomolecules─in complex biofluids remains a significant analytical hurdle, yet is critical for early and accurate disease diagnosis. These difficul...

Portable AI-driven electrochemical aptasensor for real-time Staphylococcus aureus detection in food and beverages.

Mikrochimica acta
A portable electrochemical aptasensor integrated with machine learning was developed for rapid and on-site detection of Staphylococcus aureus (S. aureus) in food and beverage samples. The aptasensor was fabricated using screen-printed carbon electrod...

Deep Learning-Enabled Unbiased Precision Toxicity Assessment of Zebrafish Organ Development.

Environmental science & technology
Precise assessment of toxicological effects remains a key bottleneck in biomedical and environmental health assessments. Traditional toxicology relies on macroscopic end points and manual image analysis, which limit sensitivity to structural damage a...

Machine learning-enabled microfluidic ratiometric fluorescence sensor array based on lanthanide-gold nanoclusters for visual detection of multicomponent antibiotics.

Biosensors & bioelectronics
The accumulation of multiple antibiotics in the environment poses severe threats to ecosystems and human health, demanding rapid, sensitive, and portable detection methods. This study introduces a lanthanide-gold nanocluster (AuNCs)-based microfluidi...