AIMC Topic: Mice, Inbred C57BL

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Deep learning-based quantification of abdominal fat on magnetic resonance images.

PloS one Sep 20, 2018
Obesity is increasingly prevalent and associated with increased risk of developing type 2 diabetes, cardiovascular diseases, and cancer. Magnetic resonance imaging (MRI) is an accurate method for determination of body fat volume and distribution. How...
Male Deep Learning Magnetic Resonance Imaging Mice, Inbred C57BL Body Weight Automation Organ Specificity Adipose Tissue Mice, Knockout Phenotype Female Animals Diet, Western Abdominal Fat Mice, Inbred C3H Intra-Abdominal Fat Apolipoproteins E Subcutaneous Fat
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DeepLabCut: markerless pose estimation of user-defined body parts with deep learning.

Nature neuroscience Aug 20, 2018
Quantifying behavior is crucial for many applications in neuroscience. Videography provides easy methods for the observation and recording of animal behavior in diverse settings, yet extracting particular aspects of a behavior for further analysis ca...
Nerve Net Behavior Transfer, Psychology Deep Learning Video Recording Odorants Behavior, Animal Psychomotor Performance Neural Networks, Computer Drosophila melanogaster Algorithms Animals Male Humans Mice Posture Mice, Inbred C57BL
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A Robotic System for Adaptive Training and Function Assessment of Forelimb Retraction in Mice.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society Aug 8, 2018
Rodent models are decisive for translational research in healthy and pathological conditions of motor function thanks to specific similarities with humans. Here, we present an upgraded version of the M-Platform, a robotic device previously designed t...
Biomechanical Phenomena Animals Male Mice Female Isometric Contraction Stroke Rehabilitation Friction Conditioning, Operant Forelimb Mice, Inbred C57BL Robotics Psychomotor Performance Cerebral Cortex
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A Novel Morphological Marker for the Analysis of Molecular Activities at the Single-cell Level.

Cell structure and function Jun 29, 2018
For more than a century, hematoxylin and eosin (H&E) staining has been the de facto standard for histological studies. Consequently, the legacy of histological knowledge is largely based on H&E staining. Due to the recent advent of multi-photon excit...
Biosensing Techniques Mice, Inbred C57BL Microscopy, Fluorescence Dogs Madin Darby Canine Kidney Cells Machine Learning Animals Single-Cell Analysis Imaging, Three-Dimensional Fluorescence Resonance Energy Transfer MAP Kinase Signaling System Mice, Transgenic
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Cell dynamic morphology classification using deep convolutional neural networks.

Cytometry. Part A : the journal of the International Society for Analytical Cytology May 15, 2018
Cell morphology is often used as a proxy measurement of cell status to understand cell physiology. Hence, interpretation of cell dynamic morphology is a meaningful task in biomedical research. Inspired by the recent success of deep learning, we here ...
Mice Mice, Inbred BALB C Mice, Inbred C57BL Lymphocytes Databases, Factual Animals Male Deep Learning Neural Networks, Computer
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Recognition of early stage thigmotaxis in Morris water maze test with convolutional neural network.

PloS one May 3, 2018
The Morris water maze test (MWM) is a useful tool to evaluate rodents' spatial learning and memory, but the outcome is susceptible to various experimental conditions. Thigmotaxis is a commonly observed behavioral pattern which is thought to be relate...
Sensitivity and Specificity Carotid Stenosis Animals Spatial Memory Taxis Response Male Mice Neural Networks, Computer Mice, Inbred C57BL Swimming Machine Learning Reaction Time Carotid Artery, Common Maze Learning
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Computational Analysis of Cell Dynamics in Videos with Hierarchical-Pooled Deep-Convolutional Features.

Journal of computational biology : a journal of computational molecular cell biology Apr 25, 2018
Computational analysis of cellular appearance and its dynamics is used to investigate physiological properties of cells in biomedical research. In consideration of the great success of deep learning in video analysis, we first introduce two-stream co...
Computational Biology Mice, Inbred BALB C Mice, Inbred C57BL Skin Diseases Skin Transplantation Cell Physiological Phenomena Lymphocytes Video Recording Algorithms Animals Neural Networks, Computer Male Mice
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Cortical frequency-specific plasticity is independently induced by intracortical circuitry.

Neuroscience letters Dec 21, 2017
Auditory learning induces frequency-specific plasticity in the auditory cortex. Both the auditory cortex and thalamus are involved in the cortical plasticity; however, the precise role of the intracortical circuity remains unclear until the contribut...
Mice, Inbred C57BL Lidocaine Neurons Auditory Cortex Animals Acoustic Stimulation Evoked Potentials, Auditory Voltage-Gated Sodium Channel Blockers Mice Electric Stimulation Neuronal Plasticity Thalamus Action Potentials
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Fully automated, deep learning segmentation of oxygen-induced retinopathy images.

JCI insight Dec 21, 2017
Oxygen-induced retinopathy (OIR) is a widely used model to study ischemia-driven neovascularization (NV) in the retina and to serve in proof-of-concept studies in evaluating antiangiogenic drugs for ocular, as well as nonocular, diseases. The primary...
Retinal Neovascularization Mice, Inbred C57BL Oxygen Observer Variation Mice, Transgenic Male Algorithms Image Processing, Computer-Assisted Deep Learning Female Microscopy, Confocal Animals Disease Models, Animal
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Inhibitory activity of linarin on osteoclastogenesis through receptor activator of nuclear factor κB ligand-induced NF-κB pathway.

Biochemical and biophysical research communications Dec 18, 2017
Linarin, a natural flavonoid glycoside widely found in plants, has been reported to possess anti-inflammation, neuroprotection and osteogenic properties. However, its impact on osteoclast remains unclear. In the present study, the effects of linarin ...
NF-kappa B Macrophages Osteogenesis Cells, Cultured RAW 264.7 Cells Animals Glycosides Osteoblasts Mice Signal Transduction RANK Ligand Mice, Inbred C57BL Dose-Response Relationship, Drug
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