AIMC Topic: Microfluidic Analytical Techniques
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Thread/paper- and paper-based microfluidic devices for glucose assays employing artificial neural networks.
Electrophoresis
May 14, 2018
This paper describes the fabrication of and data collection from two microfluidic devices: a microfluidic thread/paper based analytical device (μTPAD) and 3D microfluidic paper-based analytical device (μPAD). Flowing solutions of glucose oxidase (GOx...
Thread based electrofluidic platform for direct metabolite analysis in complex samples.
Analytica chimica acta
Oct 28, 2017
The application of electrophoresis upon commercial threads is investigated for development of low-cost diagnostics assays, designed for the matrix separation and quantification of low abundance metabolites in complex samples - in this work riboflavin...
Multiparameter mechanical and morphometric screening of cells.
Scientific reports
Dec 2, 2016
We introduce a label-free method to rapidly phenotype and classify cells purely based on physical properties. We extract 15 biophysical parameters from cells as they deform in a microfluidic stretching flow field via high-speed microscopy and apply m...
Machine Learning Based Single-Frame Super-Resolution Processing for Lensless Blood Cell Counting.
Sensors (Basel, Switzerland)
Nov 2, 2016
A lensless blood cell counting system integrating microfluidic channel and a complementary metal oxide semiconductor (CMOS) image sensor is a promising technique to miniaturize the conventional optical lens based imaging system for point-of-care test...
Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells.
Nature methods
Aug 3, 2015
Induced pluripotent stem cells (iPSCs) are an essential tool for modeling how causal genetic variants impact cellular function in disease, as well as an emerging source of tissue for regenerative medicine. The preparation of somatic cells, their repr...
Prescribed 3-D Direct Writing of Suspended Micron/Sub-micron Scale Fiber Structures via a Robotic Dispensing System.
Journal of visualized experiments : JoVE
Jun 12, 2015
A 3-axis dispensing system is utilized to control the initiating and terminating fiber positions and trajectory via the dispensing software. The polymer fiber length and orientation is defined by the spatial positioning of the dispensing system 3-axi...
Size Control in the Nanoprecipitation Process of Stable Iodine (¹²⁷I) Using Microchannel Reactor-Optimization by Artificial Neural Networks.
AAPS PharmSciTech
Feb 6, 2015
In this study, nanosuspension of stable iodine ((127)I) was prepared by nanoprecipitation process in microfluidic devices. Then, size of particles was optimized using artificial neural networks (ANNs) modeling. The size of prepared particles was eval...
Microfluidics-based label-free SERS profiling of exosomes with machine learning for osteosarcoma diagnosis.
Talanta
Nov 1, 2025
Osteosarcoma (OS) calls for early diagnosis to significantly improve patient survival rates. Exosomes hold significant potential as noninvasive biomarkers for the early diagnosis of cancer. Here, we design a microfluidic device to purify and analyze ...
Machine learning classification of quorum sensing-induced bacterial aggregation using flow rate assays on paper chips toward bacterial species identification in potable water sources.
Biosensors & bioelectronics
Sep 15, 2025
Preventing waterborne disease caused by bacteria is especially important in low-resource settings, where skilled personnel and laboratory equipment are scarce. This work reports a straightforward method for classifying bacterial species by monitoring...
Artificial intelligence enhanced microfluidic system for multiplexed point-of-care-testing of biological thiols.
Talanta
May 15, 2025
Cysteamine (CA) serves as a cystine-depleting agent employed in the management of cystinosis and a range of other medical conditions. Monitoring blood CA levels at the point of care is imperative due to the risk of toxicity associated with elevated C...
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