AIMC Topic: Middle Aged

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The parameter Houlihan: A solution to high-throughput identifiability indeterminacy for brutally ill-posed problems.

Mathematical biosciences
One way to interject knowledge into clinically impactful forecasting is to use data assimilation, a nonlinear regression that projects data onto a mechanistic physiologic model, instead of a set of functions, such as neural networks. Such regressions...

Automatic radiomic feature extraction using deep learning for angiographic parametric imaging of intracranial aneurysms.

Journal of neurointerventional surgery
BACKGROUND: Angiographic parametric imaging (API) is an imaging method that uses digital subtraction angiography (DSA) to characterize contrast media dynamics throughout the vasculature. This requires manual placement of a region of interest over a l...

Radiomics machine-learning signature for diagnosis of hepatocellular carcinoma in cirrhotic patients with indeterminate liver nodules.

European radiology
PURPOSE: To enhance clinician's decision-making by diagnosing hepatocellular carcinoma (HCC) in cirrhotic patients with indeterminate liver nodules using quantitative imaging features extracted from triphasic CT scans.

Investigation of bias in an epilepsy machine learning algorithm trained on physician notes.

Epilepsia
Racial disparities in the utilization of epilepsy surgery are well documented, but it is unknown whether a natural language processing (NLP) algorithm trained on physician notes would produce biased recommendations for epilepsy presurgical evaluation...

Using artificial intelligence to reduce diagnostic workload without compromising detection of urinary tract infections.

BMC medical informatics and decision making
BACKGROUND: A substantial proportion of microbiological screening in diagnostic laboratories is due to suspected urinary tract infections (UTIs), yet approximately two thirds of urine samples typically yield negative culture results. By reducing the ...

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA.

BMC cancer
BACKGROUND: Blood-based methods using cell-free DNA (cfDNA) are under development as an alternative to existing screening tests. However, early-stage detection of cancer using tumor-derived cfDNA has proven challenging because of the small proportion...

Deep Learning Classifiers for Automated Detection of Gonioscopic Angle Closure Based on Anterior Segment OCT Images.

American journal of ophthalmology
PURPOSE: To develop and test deep learning classifiers that detect gonioscopic angle closure and primary angle closure disease (PACD) based on fully automated analysis of anterior segment OCT (AS-OCT) images.

Applying machine learning to predict future adherence to physical activity programs.

BMC medical informatics and decision making
BACKGROUND: Identifying individuals who are unlikely to adhere to a physical exercise regime has potential to improve physical activity interventions. The aim of this paper is to develop and test adherence prediction models using objectively measured...

Scoring colorectal cancer risk with an artificial neural network based on self-reportable personal health data.

PloS one
Colorectal cancer (CRC) is third in prevalence and mortality among all cancers in the US. Currently, the United States Preventative Services Task Force (USPSTF) recommends anyone ages 50-75 and/or with a family history to be screened for CRC. To impr...