AIMC Topic: Middle Aged

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Novel composite health assessment risk model for older allogeneic transplant recipients: BMT-CTN 1704.

Blood advances
Allogeneic hematopoietic cell transplantation (allo-HCT) is potentially curative for older adults with hematologic malignancies. Concerns on nonrelapse mortality (NRM) in older adults limit allo-HCT utilization. We executed a prospective, observation...

Prediction of tissue and clinical thrombectomy outcome in acute ischaemic stroke using deep learning.

Brain : a journal of neurology
The advent of endovascular thrombectomy has significantly improved outcomes for stroke patients with intracranial large vessel occlusion, yet individual benefits can vary widely. As demand for thrombectomy rises and geographical disparities in stroke...

Artificial intelligence models using F-wave responses predict amyotrophic lateral sclerosis.

Brain : a journal of neurology
Nerve conduction F-wave studies contain crucial information about subclinical motor dysfunction that can be used to diagnose patients with amyotrophic lateral sclerosis (ALS). However, F-wave responses are highly variable in morphology, making wavefo...

Modeling the Determinants of Subjective Well-Being in Schizophrenia.

Schizophrenia bulletin
BACKGROUND: The ultimate goal of successful schizophrenia treatment is not just to alleviate psychotic symptoms, but also to reduce distress and achieve subjective well-being (SWB). We aimed to identify the determinants of SWB and their interrelation...

Protocol for a multicenter randomized controlled trial to assess the usefulness of computer-aided detection systems for colonoscopy in colorectal cancer screening in the Asia-Pacific region (project CAD/NCCH2217).

Japanese journal of clinical oncology
Ensuring the high quality of colonoscopies in colorectal cancer (CRC) screening is essential to reducing CRC. Recently, computer-aided detection systems (CADe) that use artificial intelligence have attracted much attention as potentially useful tools...

Deep learning on high-density EEG during a cognitive task distinguishes patients with Parkinson's disease from healthy controls.

Journal of neural engineering
Parkinson's disease (PD) is a neurodegenerative disorder characterized by motor and non-motor symptoms, including cognitive impairment. Its diagnosis, which used to be based on clinical assessment, increasingly relies on biomarkers. While electroence...

Geometry of orofacial neuromuscular signals: speech articulation decoding using surface electromyography.

Journal of neural engineering
In this article, we present data and methods for decoding speech articulations using surface electromyogram (EMG) signals. EMG-based speech neuroprostheses offer a promising approach for restoring audible speech in individuals who have lost the abili...

Multitask Deep Learning Based on Longitudinal CT Images Facilitates Prediction of Lymph Node Metastasis and Survival in Chemotherapy-Treated Gastric Cancer.

Cancer research
UNLABELLED: Accurate preoperative assessment of lymph node metastasis (LNM) and overall survival (OS) status is essential for patients with locally advanced gastric cancer receiving neoadjuvant chemotherapy, providing timely guidance for clinical dec...

A supervised machine learning approach for predicting the need for postsurgical intervention in acromegaly.

Neurosurgical focus
OBJECTIVE: Patients with growth hormone (GH)-secreting pituitary adenomas (PAs) experience various symptoms and comorbidities, which can ultimately lead to increased mortality. This study aimed to develop and validate a machine learning (ML) model fo...

A novel deep learning system for automated diagnosis and grading of lumbar spinal stenosis based on spine MRI: model development and validation.

Neurosurgical focus
OBJECTIVE: The study aimed to develop a single-stage deep learning (DL) screening system for automated binary and multiclass grading of lumbar central stenosis (LCS), lateral recess stenosis (LRS), and lumbar foraminal stenosis (LFS).