AIMC Topic: Middle Aged
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Accuracy and acceptability of self-sampling HPV testing in cervical cancer screening: a population-based study in rural Yunnan, China.
Scientific reports
Jul 21, 2025
To evaluate the accuracy and acceptability of self-sampling samples for HPV testing for cervical cancer screening in rural Yunnan of China. In 2022, 3000 women aged 17-69 were recruited and provided self-sampling vaginal samples alongside provider-sa...
Establishment of two pathomic-based machine learning models to predict CLCA1 expression in colon adenocarcinoma.
PloS one
Jul 21, 2025
Chloride channel accessory 1 (CLCA1) is considered a potential prognostic biomarker for colon adenocarcinoma (COAD). The objective of this research was to develop two pathomics models to predict CLCA1 expression from hematoxylin-eosin (H&E) stained p...
Identification of podocyte molecular markers in diabetic kidney disease via single-cell RNA sequencing and machine learning.
PloS one
Jul 21, 2025
Diabetic kidney disease (DKD) is a major cause of end-stage renal disease globally, with podocytes being implicated in its pathogenesis. However, the underlying mechanisms of podocyte involvement remain unclear. The aim of the present study was to id...
Analysis of aPTT predictors after unfractionated heparin administration in intensive care units using machine learning models.
PloS one
Jul 21, 2025
OBJECTIVES: Predicting optimal coagulation control using heparin in intensive care units (ICUs) remains a significant challenge. This study aimed to develop a machine learning (ML) model to predict activated partial thromboplastin time (aPTT) in ICU ...
Development and temporal validation of a nomogram for predicting ICU 28-day mortality in middle-aged and elderly sepsis patients: An eICU database study.
PloS one
Jul 21, 2025
BACKGROUND AND OBJECTIVE: Despite advances in intensive care, sepsis remains a leading cause of mortality in intensive care unit (ICU) patients, especially middle-aged and elderly individuals. Given the limitations of conventional scoring systems and...
Accurate deep-learning model to differentiate dementia severity and diagnosis using a portable electroencephalography device.
Scientific reports
Jul 20, 2025
Mild cognitive impairment (MCI) and dementia pose significant health challenges in aging societies, emphasizing the need for accessible, cost-effective, and noninvasive diagnostic tools. Electroencephalography (EEG) is a promising biomarker, but trad...
Application of machine learning algorithms and SHAP explanations to predict fertility preference among reproductive women in Somalia.
Scientific reports
Jul 20, 2025
Fertility preferences significantly influence population dynamics and reproductive health outcomes, particularly in low-resource settings, such as Somalia, where high fertility rates and limited healthcare infrastructure pose significant challenges. ...
Artificial intelligence in coronary angiography: benchmarking the diagnostic accuracy of ChatGPT-4o against interventional cardiologists.
Open heart
Jul 20, 2025
BACKGROUND: The integration of artificial intelligence (AI) into medical diagnostics has significantly impacted cardiology by enhancing diagnostic precision and therapeutic strategies. Coronary artery disease continues to be a leading cause of global...
Benchmarking
Humans
Coronary Vessels
Cardiologists
Aged
Male
Predictive Value of Tests
Middle Aged
Coronary Angiography
Generative Artificial Intelligence
Radiographic Image Interpretation, Computer-Assisted
Artificial Intelligence
Coronary Artery Disease
Retrospective Studies
Female
Reproducibility of Results
Enhancing cardiac disease detection via a fusion of machine learning and medical imaging.
Scientific reports
Jul 19, 2025
Cardiovascular illnesses continue to be a predominant cause of mortality globally, underscoring the necessity for prompt and precise diagnosis to mitigate consequences and healthcare expenditures. This work presents a complete hybrid methodology that...
Application of image guided analyses to monitor fecal microbial composition and diversity in a human cohort.
Scientific reports
Jul 19, 2025
The critical role of gut microbiota in human health and disease has been increasingly illustrated over the past decades, with a significant amount of research demonstrating an unmet need for self-monitor of the fecal microbial composition in an easil...
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