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Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learning.

Scientific reports
Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by elevated pulmonary arterial pressure, leading to right heart failure and death. Despite advancements in diagnosis and treatment, it remains incurable, and ...

Predicting outcomes following open abdominal aortic aneurysm repair using machine learning.

Scientific reports
Patients undergoing open surgical repair of abdominal aortic aneurysm (AAA) have a high risk of post-operative complications. However, there are no widely used tools to predict surgical risk in this population. We used machine learning (ML) technique...

A robotic rehabilitation intervention in a home setting during the Covid-19 outbreak: a feasibility pilot study in patients with stroke.

Journal of neuroengineering and rehabilitation
BACKGROUND: Telerehabilitation allows patients to engage in therapy away from healthcare facilities, often in the comfort of their homes. Studies have suggested that it can effectively improve motor and cognitive function. However, its applicability ...

Predicting isolated impaired glucose tolerance without oral glucose tolerance test using machine learning in Chinese Han men.

Frontiers in endocrinology
BACKGROUND: Isolated Impaired Glucose Tolerance (I-IGT) represents a specific prediabetic state that typically requires a standardized oral glucose tolerance test (OGTT) for diagnosis. This study aims to predict glucose tolerance status in Chinese Ha...

Single Joint Hybrid Assistive Limb (HAL-SJ) robotic exoskeleton therapy in improving functional outcomes among workers with wrist fractures: Study protocol for a randomized controlled trial.

PloS one
INTRODUCTION: Robotic technologies have been developed for motor rehabilitation and such robots have shown favourable results when compared with equivalent doses of usual clinical therapy. Recently, robotic interventions have been suggested to be app...

Torg-Pavlov ratio qualification to diagnose developmental cervical spinal stenosis based on HRViT neural network.

BMC musculoskeletal disorders
BACKGROUND: Developing computer-assisted methods to measure the Torg-Pavlov ratio (TPR), defined as the ratio of the sagittal diameter of the cervical spinal canal to the sagittal diameter of the corresponding vertebral body on lateral radiographs, c...

Interpretable machine learning model for predicting delirium in patients with sepsis: a study based on the MIMIC data.

BMC infectious diseases
OBJECTIVE: The aim of this study was to construct interpretable machine learning models to predict the risk of developing delirium in patients with sepsis and to explore the impact of delirium on the 28-day survival rate of patients.

Vascular-related biological stress, DNA methylation, allostatic load and domain-specific cognition: an integrated machine learning and causal inference approach.

BMC neurology
BACKGROUND: Vascular disease in aging populations spans a wide range of disorders including strokes, circulation disorders and hypertension. As individuals age, vascular disorders co-occur and hence exert combined effects. In the present study we int...

Comparison of machine learning models with conventional statistical methods for prediction of percutaneous coronary intervention outcomes: a systematic review and meta-analysis.

BMC cardiovascular disorders
INTRODUCTION: Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) models in predicting differ...