OBJECTIVE: Given the significantly increased number of individuals prescribed stimulants in the past decade, there has been growing concern regarding the risk of cardiovascular events among adults on stimulant therapy. We aimed to quantify the added ...
OBJECTIVE: Cauda equina syndrome (CES) poses significant neurological risks if untreated. Diagnosis relies on clinical and radiological features. As the symptoms are often nonspecific and common, the diagnosis is usually made after a magnetic resonan...
BMC medical informatics and decision making
Feb 20, 2025
Intracranial atherosclerotic stenosis (ICAS) refers to a narrowing of intracranial arteries due to plaque buildup on the inside of the vessel walls restricting blood flow. Early detection of ICAS is crucial to prevent serious consequences such as str...
BACKGROUND: Bladder cancer (BLCA) exists a profound molecular diversity, with basal and luminal subtypes having different prognostic and therapeutic outcomes. Traditional methods for molecular subtyping are often time-consuming and resource-intensive...
Aging clinical and experimental research
Feb 20, 2025
BACKGROUND: Sarcopenia is a common complication in patients with stroke, adversely affecting recovery and increasing mortality risk. However, no standardised tool exists for its screening in this population. This study aims to identify factors influe...
Despite the extensive research on hepatocellular carcinoma (HCC) exploring various treatment strategies, the survival outcomes have remained unsatisfactory. The aim of this research was to evaluate the ability of machine learning (ML) methods in pred...
Journal of cancer research and clinical oncology
Feb 20, 2025
PURPOSE: The International Federation of Gynecology and Obstetric (FIGO) stage is critical to guiding the treatments of ovarian cancer (OC). We tried to develop a model to predict the FIGO stage of OC through machine learning algorithms with patients...
PURPOSE: Primary barriers to application of immune checkpoint inhibitor (ICI) therapy for cancer include severe side effects (such as potentially life threatening pneumonitis [PN]), which can cause the discontinuation of treatment. Predicting which p...
Inter-individual cognitive variability, influenced by genetic and environmental factors, is crucial for understanding typical cognition and identifying early cognitive disorders. This study investigated the association between serum protein expressio...
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Feb 19, 2025
PURPOSE: Cervical cancer (CC), a common female malignancy, has been linked to alterations in DNA methylation. This study employed an integrated "dry-wet lab" strategy combining bioinformatics, machine learning, and experimental validation to identify...
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