AIMC Topic: Middle Aged

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Integrated artificial intelligence in healthcare and the patient's experience of care.

Scientific reports
Healthcare is plagued with many problems that Artificial Intelligence (AI) can ameliorate or sometimes amplify. Regardless, AI is changing the way we reason towards solutions, especially at the frontier of public health applications where autonomous ...

Preoperative prediction of major adverse outcomes after total arch replacement in acute type A aortic dissection based on machine learning ensemble.

Scientific reports
A machine learning model was developed and validated to predict postoperative complications in patients with acute type A aortic dissection (ATAAD) who underwent total arch replacement combined with frozen elephant trunk (TAR + FET), with the goal of...

Shared gene signatures and molecular mechanisms link ankylosing spondylitis and rheumatoid arthritis.

Scientific reports
Ankylosing spondylitis (AS) and rheumatoid arthritis (RA) are closely related autoimmune diseases with shared mechanisms that remain unclear. This study aims to identify shared molecular signatures and hub genes underlying the co-occurrence of AS and...

Integrated analysis of shared gene expression signatures and immune microenvironment heterogeneity in type 2 diabetes mellitus and colorectal cancer.

Scientific reports
Emerging evidence suggests a bidirectional relationship between colorectal cancer (CRC) and type 2 diabetes mellitus (T2DM), yet the shared molecular mechanisms and prognostic biomarkers remain poorly characterized. This study aimed to identify novel...

Machine learning to improve predictive performance of prehospital early warning scores.

Scientific reports
Early warning scores are used to assess acute patients' risk of being in a critical situation, allowing for early appropriate treatment, avoiding critical outcomes. The early warning scores use changes in vital signs to provide an assessment, however...

Machine learning analysis of kinematic movement features during functional tasks to discriminate chronic neck pain patients from asymptomatic controls.

Scientific reports
This study evaluated the discriminative potential of a machine learning model using movement features during functional tasks to distinguish between patients with non-traumatic chronic neck pain and asymptomatic controls. The study included patients ...

Proteomic risk scores for predicting common diseases using linear and neural network models in the UK biobank.

Scientific reports
Plasma proteomics provides a unique opportunity to enhance disease prediction by capturing protein expression patterns linked to diverse pathological processes. Leveraging data from 2,923 proteins measured in 53,030 UK Biobank participants, we develo...

Modeling the prediction of spontaneous rupture and bleeding in hepatocellular carcinoma via machine learning algorithms.

Scientific reports
This study aimed to identify the risk factors associated with spontaneous rupture and bleeding in hepatocellular carcinoma, establish a prediction model for spontaneous rupture bleeding via a machine learning algorithm, and validate and evaluate the ...

Automated classification of chondroid tumor using 3D U-Net and radiomics with deep features.

Scientific reports
Classifying chondroid tumors is an essential step for effective treatment planning. Recently, with the advances in computer-aided diagnosis and the increasing availability of medical imaging data, automated tumor classification using deep learning sh...

Identifying ovarian cancer with machine learning DNA methylation pattern analysis.

Scientific reports
The majority of patients with epithelial ovarian cancer (EOC) continue to be diagnosed at an advanced stage despite great advances in this disease treatment. To impact overall survival, we need better methods of EOC early diagnosis. We performed a ca...