AIMC Topic: Middle Aged

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Clinical validation of a deep learning based application for quantitative assessment of dental plaque in fluorescence imaging.

Clinical oral investigations
AIM: Evaluating dental plaque is a fundamental task for periodontal health care, but it is subjective, time-consuming, and cumbersome. Therefore, this study aimed to develop and validate a web-based deep learning application capable of objectively qu...

Development of a predictive model for distant metastasis in HCC patients post-TACE using clinical data, radiomics, and deep learning.

Journal of cancer research and clinical oncology
PURPOSE: Hepatocellular carcinoma (HCC) is a perilous malignant tumor, and transcatheter arterial chemoembolization (TACE) is a widely adopted treatment technique for advanced HCC. Nevertheless, TACE may not effectively reduce the risk of distant met...

Development of a prostate cancer biochemical recurrence risk signature using machine learning and motor protein-related genes.

PloS one
BACKGROUND: Motor proteins play significant roles in cancer progression, but their involvement in biochemical recurrence (BCR) of prostate cancer remains unclear. The objective of the study is to develop a prognostic indicator for BCR using machine l...

Multimodal MRI analysis selecting key brain features for machine learning based classification of diabetic neuropathic pain and phenotypes.

Journal of the neurological sciences
Cerebral alterations are associated with diabetic peripheral neuropathy (DPN) and neuropathic pain, including reductions in brain volumes, cortical thickness, sulcus depth, and alterations in metabolites and functional connectivity. This study combin...

Clinical parameters-based machine learning models for predicting intraoperative hemodynamic instability in hypertensive pheochromocytomas and paragangliomas patients.

World journal of urology
PURPOSE: To create machine learning (ML) models based on inflammatory markers and coagulation parameters for predicting intraoperative hemodynamic Instability (HI) in sustained hypertensive patients with pheochromocytomas and paragangliomas (PPGLs).

Genetic algorithm-optimized neural network outperforms TNM staging in predicting rapidly progressive nasopharyngeal carcinoma: Reassessing adjuvant chemotherapy benefit via propensity score matching.

European journal of cancer (Oxford, England : 1990)
PURPOSE: To establish machine learning-based predictive models for rapidly progressive nasopharyngeal carcinoma (RP-NPC), defined as disease progression within 24 months post-initial treatment, and to assess differential survival benefits of adjuvant...

Immune-enhanced machine learning approach for early detection of precancerous colorectal neoplasia: Insights from biomarkers in routine health checkups.

European journal of cancer (Oxford, England : 1990)
BACKGROUND AND AIMS: Current screening strategies for colorectal cancer (CRC) rely on colonoscopy, an invasive procedure with limited capacity to address individual risk. There is growing interest in integrating noninvasive immune biomarkers to impro...

Quercetagetin alleviates ischemic stroke injury by preserving macrophage/microglia homeostasis via inhibiting ACP5.

Phytomedicine : international journal of phytotherapy and phytopharmacology
BACKGROUND: The proinflammatory response triggered by macrophages/microglia plays a crucial role in the prognosis of acute ischemic stroke (AIS). Identifying novel targets to regulate the homeostasis of these cells is essential. Developing therapeuti...

Prediction Model of Intradialytic Hypertension in Hemodialysis Patients Based on Machine Learning.

Journal of medical systems
The escalating global burden of chronic kidney disease (CKD), particularly end-stage renal disease (ESRD), has intensified reliance on hemodialysis (HD), imposing substantial financial and operational burdens on healthcare systems and patients. Intra...